四肢洗方对糖尿病周围神经病变患者的疗效观察  

Clinical effect of limb washing prescription on the patients of diabetic peripheral neuropathy

作　　者：许迎烈 曾艺鹏 贺艳菊 徐成兴 

机构地区：[1]上海市浦东医院中医内科,201399 [2]上海市浦东医院内分泌科,201399

出　　处：《检验医学与临床》2017年第21期3160-3162,共3页Laboratory Medicine and Clinic

基　　金：上海市浦东新区中青年骨干培养资助项目(PDZYXK-5-2014021)

摘　　要：目的研究四肢洗方治疗糖尿病周围神经病变的临床效果,为该类糖尿病并发症的治疗提供依据。方法选取2014年2月至2016年4月该院入院治疗的180例糖尿病周围神经病变患者进行研究,随机分为对照组和观察组,每组各90例。对照组给与腺苷钴胺治疗;观察组患者在对照组药物治疗基础上加用四肢洗方足浴治疗。记录并比较2组患者治疗前后神经病变主觉症状问卷(TSS)评分、中医证候积分、神经传导速度变化、震感阈值,比较临床总有效率。结果与治疗前比较,2组患者治疗后的TSS评分中疼痛、麻木、感觉异常和灼烧感评分均明显降低,且治疗后观察组评分降低幅度大于对照组,差异均有统计学意义(P<0.05)。观察组患者中医证候积分下降幅度更大,治疗后的中医证候积分明显低于对照组,差异有统计学意义(P<0.05)。与治疗前比较,2组患者的腓神经、腓总神经、腓浅神经及腓肠神经传导速度均明显提升,观察组患者提升速度明显高于对照组,差异均有统计学意义(P<0.05)。2组患者震感阈值比较中,观察组患者临床总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论四肢洗方治疗糖尿病周围神经病变临床效果明显,可明显改善患者中医证候积分,提升神经传导速度,临床总有效率更高,优于单纯药物治疗,值得推广应用。Objective To study the clinical effect of the treatment of diabetic peripheral neuropathy with limb washing prescription,so as to provide basis for the treatment of diabetic complications.Methods 180 cases of diabetic patients in the hospital from February 2014 to Apriil 2016 year in hospital treatment of peripheral neuropathy were studied,were randomly divided into two groups,90 cases in each group.The control group was given Cobamamide therapy,patients in the observation group combined with limb washing foot bath treatment.Total symptoms scores（TSS）,TCM syndrome integral nerve conduction velocity,VPT were recorded to compare total clinical efficiency ratio.Results Compared with before treatment,two groups＇TSS scores of patients with pain,numbness,paresthesia and burning were significantly reduced,the scores of observation group were lower than the control group after treatment,the differences were statistically significant（P〈0.05）.Compared with before treatment,TCM syndrome integral of two groups of patients before and after treatment were significantly decreased,and the patients in the observation group were integral a drop score after treatment was significantly lower than the control group,the difference between the two groups significantly,the difference was statistically significant（P〈0.05）;Compared with before treatment,two groups of patients with peroneal nerve,common peroneal nerve and superficial peroneal nerve and sural nerve conduction velocity was significantly improved,and the patients in the observation group improved speed significantly higher than the control group,the difference was statistically significant（P〈0.05）.In the comparison of clinical effect of VPT,the ratio of observation group was higher than control group,the difference was statistically significant（P〈0.05）.Conclusion The limbs wash clinical effect in treatment of diabetic peripheral neuropathy significantly improve the TCM syndrome integral,improve nerve conduction velocity,the total clinical efficie

关 键 词：四肢洗方 糖尿病神经病变 腺苷钴胺 临床观察 

分 类 号：R587.2[医药卫生—内分泌]