无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病(COPD)急性加重期呼吸衰竭患者的临床疗效  

Clinical efficacy of noninvasive ventilator combined with naloxone in treatment of patients with acute exacerbation of respiratory failure in COPD

作　　者：赵敏[1] 

机构地区：[1]上海中医药大学附属曙光医院感染科,上海200021

出　　处：《吉林医学》2017年第11期2062-2063,共2页Jilin Medical Journal

摘　　要：目的:探讨无创呼吸机和纳洛酮联用治疗慢性阻塞性肺疾病(COPD)急性加重期呼吸衰竭的临床优势。方法:选取60例慢性阻塞性肺疾病(COPD)急性加重期呼吸衰竭患者为研究对象,随机分为联合组和对照组,各30例,联合组应用无创呼吸机联合纳洛酮治疗,对照组应用单纯采用无创呼吸机治疗,对比两组治疗效果。结果:联合组治疗有效率为100%,对照组治疗有效率为83.33%,两组治疗后动脉血氧分压、动脉血二氧化碳分压以及FEV1指标差异具有统计学意义(P<0.05)。结论:慢性阻塞性肺疾病(COPD)急性加重期呼吸衰竭患者病情危急,多为老年患者,无创呼吸机是临床常用治疗方法,在此基础上加用纳洛酮治疗,患者的临床症状缓解效果更高,对患者的预后有极大的帮助作用,值得临床应用。Objective To explore the clinical advantages of noninvasive ventilator combined with naloxone in treatment of acute exacerbation of COPD respiratory failure. Method 60 cases of chronic respiratory failure in acute exacerbations of COPD patients were selected and randomly divided into combined group and control group,30 patients in each group,combined group application of noninvasive ventilator combined with naloxone in the treatment group,compared with single pure with noninvasive ventilator therapy,compared two groups of treatment effect. Results The effective rate of the combined group was 100%,and that of the contrast group was about 83. 33%,and the difference of arterial oxygen partial pressure,arterial partial pressure of carbon dioxide and FEV1 was significantly different between the two groups（ P〈0. 05）. Conclusion COPD acute exacerbation stage of chronic respiratory failure in patients with critical for elderly patients with noninvasive ventilator is commonly used in clinical treatment,based on the use of naloxone in the treatment of patients with clinical symptoms,alleviate the effects of higher,have a great help for the prognosis of patients,worthy of clinical application.

关 键 词：慢性阻塞性肺疾病(COPD) 急性加重期呼吸衰竭 无创呼吸机 纳洛酮 

分 类 号：R563[医药卫生—呼吸系统]