RDW、CysC、FBG、HbA1c与2型糖尿病视网膜病变的关系  

Relationship RDW、Cys C、FBG、HbA1c and diabetic retinopathy with type 2 diabetes mellitus patients

作　　者：黄秋菊[1] 赖璐华[1] Huang Qiuju;Lai Luhua(Department of Endocrinology,Liu Zhou General Hospital,Guangxi 545006,Chin)

机构地区：[1]柳州市人民医院内分泌科,广西545006

出　　处：《现代医药卫生》2017年第21期3272-3274,共3页Journal of Modern Medicine & Health

基　　金：广西壮族自治区卫生厅自筹课题资助项目(Z2011283);2013年柳州市科技计划项目(2013J030402)

摘　　要：目的探讨2型糖尿病(T2DM)患者胱抑素C(Cys C)、红细胞分布宽度(RDW)、空腹血糖(FBG)、糖化血红蛋白(HbA1c)与糖尿病视网膜病变(DR)的关系。方法将2011年8月至2016年8月该院收治的126例T2DM患者分为无DR组(A组,n=43)、DR背景期组(B组,n=50)、DR增殖期组(C组,n=33)。检测3组患者RDW、Cys C、FBG、HbA1c,并进行统计学分析。结果B、C组患者RDW、Cys C、FBG、HbA1c水平均高于A组,差异均有统计学意义(P<0.05)。RDW、Cys C、FBG、HbA1c均与DR的发生呈正相关(r=0.389、0.604、0.511、0.577,P<0.05)。结论 RDW、Cys C、FBG、HbA1c可作为DR发生、发展的危险因素,在DR早期诊断中有重要价值。Objective To discuss the relationship red blood cell distribution width（RDW）,serum cystatin C（Cys C）,fasting blood glucose（FBG）,glycosylated hemoglobin（HbA1 c）and diabetic retinopathy（DR）in type 2 diabetic mellitus（T2 DM）patients. Methods A tatal of 126 patients with T2 DM in the hospital from August 2011 to August 2016 were divided into group A（without DR,n=43）,group B（background DR,n=50）,group C（proliferative DR,n=33）. RDW,Cys C,FBG and HbA1 c of three groups were detected,and statistical analysis was conducted. Results The levels of RDW,Cys C,FBG and HbA1 c of group B,C were obviously higher than those of group A,the differences were statistically significant（ P〈0. 05）. RDW, Cys C, FBG and HbA1 c were positively correlated with the occurrence of DR（r=0.389、0.604、0.511、0.577,P〈0.05）. Conclusion RDW,Cys C,FBG and HbA1 c can be used as risk factors for the development of DR. Detection of RDW,Cys C,FBG and HbA1 c is helpful for early diagnosis and development of DR with T2 DM.

关 键 词：糖尿病视网膜病变 糖尿病 2型 红细胞 半胱氨酸蛋白酶抑制剂 血糖 血红蛋白A 糖基化 红细胞分布宽度 

分 类 号：R587.2[医药卫生—内分泌]