温经通络方加减联合针灸改善颈椎病患者ESR、Fib及血液流变学指标的分析  

Analysis on modified Wenjingtongluo Decoction combined with acupuncture and moxibustion for improving ESR,Fib and hemorheology indexes in patients with cervical spondylosis

作　　者：许明山 赵燕 

机构地区：[1]莱芜市中医医院疼痛科,山东莱芜271199 [2]莱芜市中医医院脾胃病科,山东莱芜271199

出　　处：《国际检验医学杂志》2017年第21期2968-2971,共4页International Journal of Laboratory Medicine

基　　金：国家自然科学基金资助项目(81072962)

摘　　要：目的观察温经通络方加减联合针灸对颈椎病患者红细胞沉降率(ESR)、纤维蛋白原(Fib)及血液流变学指标的影响。方法选取2010年3月至2015年3月颈椎病患者112例,分为西医组和综合治疗组,每组各56例。西医组采用西医治疗,综合治疗组在西医治疗基础上辅助温经通络方加减联合针灸治疗。对比分析两组ESR、Fib、C反应蛋白(CRP)、红细胞比容(PCV)、疼痛视觉模拟评分(VAS)、血液流变学指标及疗效变化。结果综合治疗组治疗后2周ESR、Fib、CRP、PCV水平和VAS评分均明显低于西医组(P<0.05);综合治疗组治疗后2周全血高切还原黏度、全血低切还原黏度、血浆黏度、红细胞聚集指数、红细胞电泳时间和血小板电泳时间均明显低于治疗前(P<0.05),而西医组治疗前、后比较差异无统计学意义(P>0.05);综合治疗组治愈率和总有效率分别为37.50%、94.64%,西医组治愈率和总有效率分别为17.86%、80.36%,差异有统计学意义(P<0.05)。结论温经通络方加减联合针灸能显著改善颈椎病患者临床症状,值得临床推广应用。Objective To observe the effect of Wenjingtongluo Decoction combined with acupuncture and moxibustion on erythrocyte sedimentation rate（ESR）,fibrinogen（Fib）and hemorheology indicators in the patients with cervical spondylosis.Methods112 patients with cervical spondylosis from March 2010 to March 2015 were selected and divided into the Western medicine group and comprehensive treatment group,56 cases in each group.The Western medicine group adopted the Western medicine treatment,while on this basis the comprehensive treatment group was assisted by the modified Wenjingtongluo Decoction plus acupuncture and moxibustion.The changes of ESR,Fib,C reactive protein（CRP）,hematocrit（PCV）,pain visual analogue scale（VAS）and hemorheology indicators and curative effect were analyzed and compared between the two groups.Results The levels of CRP,ESR,Fib,PCV and VAS after 2-week treatment in the comprehensive treatment group were significantly lower than those in the Western medicine group（P0.05）;the whole blood high shear reduced viscosity,whole blood low shear reduced viscosity,plasma viscosity,erythrocyte aggregation index,erythrocyte electrophoresis time and platelet electrophoresis time after 2-week treatment in the comprehensive treatment group were significantly lower than those before treatment（P0.05）,while which in the Western medicine group had no statistical difference between before and after treatment（P0.05）;the cure rate and total effective rate in the comprehensive treatment group were 37.50% and 94.64% respectively,which in the Western medicine group were 17.86% and80.36% respectively,the difference was statistically significant（P0.05）.Conclusion Modified Wenjingtongluo Decoction combined with acupuncture and moxibustion can significantly improve the clinical symptoms in the patients with cervical spondylosis and is worth clinical promotion and appliaction.

关 键 词：温经通络方 针灸 颈椎病 红细胞沉降率 纤维蛋白原 血液流变学 

分 类 号：R274.9[医药卫生—中西医结合]