益坤宁胶囊的质量标准研究  

The quality standard of Yikunning Capsules

作　　者：孟正 崔平 张明 

机构地区：[1]西安阿房宫药业股份有限公司,西安710018 [2]陕西省食品药品监督检验研究院,西安710065 [3]西安大唐制药集团有限公司,西安710075

出　　处：《西北药学杂志》2017年第6期687-689,共3页Northwest Pharmaceutical Journal

基　　金：陕西省社会发展科技攻关项目(编号:2015SF246)

摘　　要：目的建立益坤宁胶囊的质量标准。方法采用TLC法鉴别当归、川芎、延胡索和香附,同时采用HPLC法对芍药苷进行含量测定。结果 TLC法鉴别斑点清楚,特征明显,阴性无干扰;含量测定方法专属性、线性、精密度和稳定性良好,平均回收率为99.0%,RSD值为0.2%(n=9)。结论建立的益坤宁胶囊的质量标准指标明确、方法可行,可有效控制本品的质量。Objective To establish the quality standard of Yikunning Capsules.Methods Angelica sinensis Radix,Chuanxiong Rhizoma,Corydalis Rhizoma and Cyperi Rhizoma in the medicine were identified by TLC.The content of paeoniflorin was determined by HPLC.Results The spots in TLC was clear and obvious without interference.The content determination method was specific,precise,accurate and stable.The recovery rate was 99.0%,RSD=0.2%（n=9）.Conclusion The established method of the quality standard of Yikunning Capsules was feasible,and can effectively control the quality of this product.

关 键 词：益坤宁胶囊 TLC法 HPLC法 

分 类 号：R282[医药卫生—中药学]