称量法测定人血清密度及不确定度评定  

Determination and evaluation measurement uncertainty of human serum sensity by weighing method

作　　者：陈峰[1,2] 陶赟[1] 戴绘芬[3] 于书平 王惠民 

机构地区：[1]南通大学附属医院检验科,江苏南通226601 [2]南通出入境检验检疫局,江苏南通226601 [3]海安县中医院检验科,江苏南通226600

出　　处：《中国卫生检验杂志》2017年第20期2968-2970,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨称量法测定人血清密度的不确定度评定方法。方法应用称量法测定人血清密度,分析各不确定度分量的来源,并对各不确定度分量分别进行评定,计算合成标准不确定度和扩展不确定度。结果总蛋白(TP)为63.2 g/L的血清密度的合成标准不确定度为0.047 4 g/L,取包含因子(k)=1.96、95%置信区间,则扩展不确定度为0.093 g/L。结论应用称量法测定人血清密度建立的测量不确定度评定方法,可满足临床参考实验室对血清密度参考测量系统的要求。Objective To evaluate the uncertainty in the determination of human serum density by weighing method.Methods The density of human serum was determined by weighing method,and all the sources of the uncertainty factors were analyzed. The uncertainties were evaluated separately,and the combined standard uncertainty and extended uncertainty were calculated. Results The standard uncertainty was 0. 047 4 g/L for serum with TP concentration of 63. 2 g/L,and the uncertainty was 0. 093 g/L with the inclusion factor（ k） = 1. 96. Conclusion The method of measuring uncertainty in the measurement of human serum density by weighing method can meet the requirement of reference density measurement system in clinical laboratories.

关 键 词：测量不确定度 血清密度 测量不确定度表示指南 

分 类 号：R446.1[医药卫生—诊断学]