早发性卵巢功能不全患者应用卵胞浆内单精子显微注射-胚胎移植获妊娠分娩1例及文献复习  

Successful pregnancy following intracytoplasmic sperm injection-embryo transfer in a patient with premature ovarian insufficiency:a case report

作　　者：马伟旭 陈薪[1] 周星宇[1] 李雪兰[1] 陈婉乐 叶德盛[1] 陈士岭[1] 

机构地区：[1]南方医科大学南方医院妇产科生殖医学中心,广东广州510515

出　　处：《南方医科大学学报》2017年第10期1418-1422,共5页Journal of Southern Medical University

基　　金：国家自然科学基金(81671524;81401177);广东省省级科技计划项目(2016A020218009);广东省自然科学基金(2015A030313286);南方医科大学临床研究项目(LC2016ZD010)~~

摘　　要：报道1例早发性卵巢功能不全患者在长期密切监测过程中出现卵巢功能的波动,并行多次卵胞浆内单精子显微注射-胚胎移植治疗,最终获得临床妊娠和分娩的病例并进行相关文献复习。提示对于较年轻、有强烈生育愿望的早发性卵巢功能不全患者,应该在排除禁忌症后尽早开始激素替代治疗,积极进行辅助生殖助孕,仍有望在卵巢功能完全耗竭之前获得正常妊娠分娩。We report（POI）.a case of ovarian finally function obtained fluctuation clinical during long-term with follow-up in a patient with premature delivery ovarian several insufficiency The sperm patient pregnancy subsequent uneventful full-term after intracytoplasmic（HRT）injection-embryo transfer should（ICSI-ET）be cycles.as This case demonstrates that hormone replacement POI therapy and for the assisted reproductive therapy applied soon as possible to young such patients with who have and a strong desire before pregnancy exhaustion in of the absence of contraindications.This strategy helps patients obtain pregnancy delivery ovarian function.

关 键 词：早发性卵巢功能不全 激素替代治疗 卵胞浆内单精子显微注射-胚胎移植 分娩 

分 类 号：R714.8[医药卫生—妇产科学]