2011-2015年我国结核菌/艾滋病病毒双重感染患者治疗管理情况  

Treatment of TB/HIV co-infection patients in China from 2011 to 2015

作　　者：薛晓[1,2] 刘二勇[1] 周林[1] 

机构地区：[1]中国疾病预防控制中心结核病预防控制中心,北京102206 [2]北京市丰台区疾病预防控制中心,北京100071

出　　处：《中国艾滋病性病》2017年第9期817-820,共4页Chinese Journal of Aids & STD

摘　　要：目的了解2011-2015年中国结核菌(TB)/艾滋病病毒(HIV)(简称TB/HIV)双重感染患者的治疗管理情况。方法利用2011-2015年结核菌/艾滋病病毒防治工作年报数据,采用描述性流行病学方法,分析5年全国TB/HIV双重感染患者中,同时开展抗结核治疗和抗病毒治疗的比例,分析上一年度登记的双重感染患者抗结核治疗的成功率、病死率。将全国31个省分为既往执行过全球基金的项目省和非项目省,比较三个指标(同时开展抗结核和抗病毒治疗的比例、抗结核治疗的成功率和病死率)的不同。结果 2011-2015年,TB/HIV双重感染患者同时开展抗结核和抗病毒治疗的比例5年平均为63.22%;上一年度登记双重感染患者抗结核治疗的成功率5年平均为88.75%,病死率5年平均为4.45%。全球基金项目省三个指标分别为64.02%,89.50%、4.14%;非项目省三个指标分别为59.75%、80.11%、8.10%。结论中国TB/HIV双重感染患者同时开展抗结核和抗病毒治疗的比例较低,抗结核治疗成功率较低,病死率高。应该分析原因,提高工作质量,改善双重感染患者的生命质量。项目省开展的患者治疗管理工作的质量要优于非项目省,应加强对非项目省双重感染防治工作的支持。Objective To understand the treatment and management of TB/HIV coqnfection patients in China. Methods Annual reports were collected from 2011 to 2015. Descriptive epidemiological method was used to analyze the proportion of anti-tuberculosis treatment and antiretroviral therapy （ART） in TB/HIV co-infection patients, with success rate of anti-tuberculosis treatment and mortality of patients registered in the previous year. 31 provinces were divided into Global Fund （GF） program provinces and non-GF provinces. Difference of the three indexes was compared between the two classes. Results From 2011 to 2015, the average proportion of anti-tuberculosis treatment and ART in TB/HIV coqnfection patients was 63.22%. The average treatment success rate of patients registered in the previous year was 88. 75%and the mortality was 4.45%. In GF provinces, the average proportion of anti-tuberculosis treatment and ART, treatment success rate and mortality were 64.02%, 89. 50% , and 4.14% respectively. The three indexes in non-GF provinces were 59.75%, 80.11%, and 8.10% respectively. Conclusion The average proportion of anti-tuberculosis treatment and ART is low as well as the success rate of anti-tubercu- losis treatment, and the mortality is high. Work quality in GF provinces is better than that in non-GF provinces. Causes should be analyzed so as to improve the quality of treatment services and to enhance the life quality of TB/ HIV co-infection patients.

关 键 词：结核菌/艾滋病病毒双重感染 抗结核治疗 抗病毒治疗 治疗转归 全球基金项目省 

分 类 号：R512.91[医药卫生—内科学] R52[医药卫生—临床医学]