羊水粪染胎盘临床病理分析  

Clinicopathological analysis of meconium stained placenta

作　　者：冯瑶 肖虹[2] 郑绘霞[2] 阴琰[2] 梁钢[2] 

机构地区：[1]山西医科大学第一临床医学院,太原030001 [2]山西医科大学第一医院病理科,太原030001

出　　处：《临床与病理杂志》2017年第10期2125-2129,共5页Journal of Clinical and Pathological Research

摘　　要：目的:探讨羊水粪染胎盘的病理改变及其与妊娠结局之间的关系。方法:收集80例羊水粪染胎盘与80例无羊水粪染胎盘的病理及相关临床资料,观察显微镜下两组胎盘的病理改变,分析其病理改变与妊娠结局的关系。结果:与对照组相比,观察组胎盘病理改变(绒毛膜羊膜炎、合体细胞结节增多、绒毛间质纤维化等)发生率明显升高(P<0.05);观察组不良妊娠结局(胎儿窘迫、吸入性肺炎、新生儿窒息等)的发生率明显高于对照组(P<0.05)。结论:羊水粪染胎盘的病理改变与不良妊娠结局关系密切。对羊水粪染的产妇常规行胎盘病理检查,可以指导临床对产妇及新生儿的诊断与治疗。Objective： To investigate the pathological changes of placenta and its relationship with pregnancy outcome. Methods： The clinicopathological data of 80 cases of amniotic fluid stained placenta and 80 cases without amniotic fluid stained placenta were collected. The pathological changes of placenta under microscope in the two groups were observed, and the relationship between pathological changes and pregnancy outcome was analyzed. Results： Compared with the control group, the change in the observation group （placenta chorioamnionitis, syncytiotrophoblast nodules increased, villous interstitial fibrosis incidence rate） were more obvious, the difference was statistically significant （P〈0.05）; the incidence rate of the adverse pregnancy outcomes in the observation group （fetal distress, neonatal asphyxia, aspiration pneumonia, etc.） was higher than that in the control group, the difference was statistically significant （P〈0.05）. Conclusion： The pathological changes of placenta with meconium stained amniotic fluid are closely related to the adverse pregnancy outcome. Routine examination of placental pathology in meconium stained amniotic fluid can guide the diagnosis and treatment of maternal and neonatal diseases.

关 键 词：羊水粪染 胎盘病理 妊娠结局 

分 类 号：R714.2[医药卫生—妇产科学]