慢性肺源性心脏病患者采用安体舒通、托拉塞米治疗效果探究  

Study on the therapeutic effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease

作　　者：曾省都[1] 吴国斌[1] 

机构地区：[1]江西省赣南医学院第一附属医院呼吸内科,江西赣州341000

出　　处：《中国当代医药》2017年第30期83-85,共3页China Modern Medicine

基　　金：江西省赣州市指导性科技计划项目(GZ2014ZSF021)

摘　　要：目的探讨慢性肺源性心脏病患者采用安体舒通和托拉塞米治疗的临床效果。方法选取2015年6月~2016年12月我院收治的72例慢性肺源性心脏病患者作为研究对象,按照随机数表法,将患者均分为对照组和观察组,每组患者36例。对照组患者采取强心剂及利尿剂等常规方法治疗,观察组患者在对照组的基础上采用安体舒通及托拉塞米进行治疗。比较两组患者的治疗效果以及心功能分级情况。结果观察组患者的治疗总有效率(97.22%)明显高于对照组(83.33%),差异有统计学意义(P<0.05)。治疗前后,两组患者的心功能分级情况比较,差异均无统计学意义(P>0.05)。对照组患者治疗后的Ⅱ级例数多于治疗前,Ⅳ级例数少于治疗前,差异有统计学意义(P<0.05)。观察组患者治疗后的两组患者的Ⅱ级例数多于治疗前,Ⅲ、Ⅳ级例数少于治疗前,差异有统计学意义(P<0.05)。结论在使用强心剂及利尿剂的基础上应用安体舒通和托拉塞米对慢性肺源性心脏病患者进行治疗,可以有效改善患者心功能症状,降低心功能分级,提高治疗效果。Objective To investigate the clinical effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease.Methods A total of 72 patients with chronic pulmonary heart disease who treated in our hospital from June 2015 to December 2016 were selected as objects and were randomly divided into control group and observation group according to the random number table method.There were 36 patients in each group.The control group was treated with Tonic and Diuretic and other conventional methods.The observation group was treated with Spironolactone and Torasemide on the basis of the control group.The clinical curative effect and cardiac function were compared between the two groups.Results The total effective rate in the observation group was 97.22% and 83.33% in the control group,the difference was statistically significant （P〈0.05）.Before treatment and after treatment,the cardiac function grading of the two groups was compared,the differences were not statistically significant （P〉0.05）.After treatment,the patients of Ⅱ level in the control group was more than before treatment,the patients of Ⅳ level was less than before treatment,the difference was statistically significant （P〈0.05）.After treatment,the patients of Ⅱ level in the observation group was more than before treatment,the patients of m and Ⅳ level were less than before treatment,the difference was statistically significant （P〈0.05）.Conclusion The treatment of patients with chronic pulmonary heart disease by using Spironolactone and Tolosemide on the basis of the use of Tonic and Diuretics can effectively improve the patients＇ cardiac function,reduce the grade of cardiac function and improve the therapeutic effect.

关 键 词：慢性肺源性心脏病 安体舒通 托拉塞米 临床效果 

分 类 号：R541.6[医药卫生—心血管疾病]