降钙素原与早产低出生体重儿医院感染败血症的关系研究  

Relationship between procalcitonin and nosocomial sepsis in preterm infants with low birth weight

作　　者：赵香丽 王月娥 胡美莲 

机构地区：[1]山东省东明县妇幼保健院,274500

出　　处：《中国社区医师》2017年第33期126-127,共2页Chinese Community Doctors

摘　　要：目的:探讨降钙素原(PCT)与早产低出生体重儿医院感染败血症的关系及临床价值。方法:收治早产低出生体重儿医院感染败血症患儿(观察组)和无感染败血症的患儿(对照组)各36例,治疗前后抽取静脉血检测超敏C反应蛋白和降钙素原水平。结果:观察组PCT与hs-CRP水平明显高于对照组(P<0.05);PCT诊断败血症的特异性、敏感性、准确性、阳性和阴性预测值高于hs-CRP(P<0.05);治疗后观察组PCT水平下降,新生儿危重症评分(NCIS)升高,与治疗前比较,差异有统计学意义(P<0.05)。结论:早产低出生体重儿医院感染败血症患儿PCT水平明显升高,这一指标可对败血症病情危重程度进行评估,且诊断败血症的准确性较高。Objective：To investigate the relationship between procalcitonin and nosocomial sepsis in low birth weight infants and its clinical value.Methods：The hospital infection in children with septicemia were prematurity and low birth weight infants（the observation group） and no septicemia patients（the control group）,with 36 cases in each group,then their venous blood were taken before and after the treatment,to detecte high sensitive C reactive protein and procalcitonin levels.Results：PCT and hs-CRP in the observation group were significantly higher than in the control group（P〈0.05）;PCT diagnosis of septicemia in specificity,sensitivity,accuracy,positive and negative predictive value is higher than hs-CRP（P〈0.05）;PCT levels decreased the observation group after the treatment,neonatal critical illness score（NCIS） increased significantly,and the differences were statistically significant when compared with before the treatment（P〈0.05）.Conclusion：The level of PCT in children with low birth weight and hospital acquired sepsis is obviously higher,which can be used to evaluate the severity of sepsis,and the accuracy of diagnosis of sepsis is higher.

关 键 词：早产 低体重儿 败血症 降钙素原 

分 类 号：R722.6[医药卫生—儿科]