鼻内镜下蝶腭孔神经阻断治疗持续性变应性鼻炎  

Endoscopic transnasal palatal nerve block for persistent allergic rhinitis

作　　者：王庭阔 刘荣 聂智樱 张伟强 杨党卫 李建兴 WANG Ting kuo;LIU Rong;NIE Zhi ying;ZHANG Wei qiang;YANG Dang wei;LI Jian xing(Department of Otorhinolaryngology,Longhua Central Hospital Affiliated to Guangdong Medical University,Shenzhen Guangdong 518110,China;Department of Health Center,Longhua Central Hospital Affiliated to Guangdong Medical University,Shenzhen Guangdong 518110,China)

机构地区：[1]广东医科大学附属深圳龙华中心医院耳鼻喉科,广东深圳518110 [2]广东医科大学附属深圳龙华中心医院保健中心,广东深圳518110

出　　处：《局解手术学杂志》2017年第11期845-848,共4页Journal of Regional Anatomy and Operative Surgery

基　　金：深圳市科创委课题(JCYJ20140415091613069);清远市科技局课题(2011 B011112082)

摘　　要：目的评估鼻内镜下蝶腭孔神经阻断对持续性变应性鼻炎的临床疗效。方法将2013年10月至2015年2月在广东医科大学附属龙华中心医院就诊的17岁以上的持续性性变应性鼻炎患者123例,经患者知情同意后分为观察组和对照组。观察组(72例)进行经鼻内镜下蝶腭孔神经阻断鼻后神经及翼管神经,对照组(51例)采用药物保守治疗。应用鼻炎生存质量(RQLQ)和视觉模拟量表(VAS)来评估治疗前、治疗后6个月、1年和2年的患者的生存质量。结果通过对106例病例进行术后随访2年,观察组治疗前RQLQ评分为(2.39±0.43)分,VAS评分为(7.45±1.24)分;治疗后6个月RQLQ和VAS的平均得分为(0.82±0.38)分、(2.47±1.42)分;治疗后1年RQLQ和VAS评分为(0.93±0.41)分、(2.53±1.54)分;治疗后2年RQLQ和VAS评分为(1.05±0.47)分、(2.67±1.69)分,差异均具有统计学意义(P<0.05);对照组治疗前后RQLQ和VAS评分差异无统计学意义(P>0.05)。结论鼻内镜下蝶腭孔神经阻断能有效提高持续性变应性鼻炎患者的生存质量,是治疗持续性变应性鼻炎安全、有效手段。ObjectiveTo evaluate the clinical efficacy of endoscopic transnasal palatal nerve block for persistent allergic rhinitis.Methods123 patients with heavy persistent allergic rhinitis who aged over 17 years old in Longhua central hospital affiliated to Guangdong medical university from October 2013 to February 2015 were divided into observation group and control group.The patients in the observation group（72 cases） were blocked with endoscopic sphenopalatine,the control group（51 cases） treated with medicine.The rhinoconjunctivitis quality of life questionnaire（RQLQ） and VAS were assessed before and after treatment for 6 months,1 year and 2 year survival.Results106 patients were followed up for 2 years.In observation group,the average score of RQLQ and VAS before treatment were （2.39±0.43）,（7.45±1.24） respectively;6 months after treatment,the average scores of RQLQ and VAS were （0.82±0.38）,（2.47±1.42） respectively;1 years （0.93±0.41） and （2.53±1.54）;2 years （1.05±0.47） and （2.67±1.69）;the differences were statistically significant（P〈0.05）.The control group showed no obvious difference in RQLQ and VAS before and after treatment.ConclusionEndoscopic sphenopalatine nerve block can effectively improve the quality of life of patients with persistent rhinitis allergic,which is safe and effective in the treatment of severe persistent allergic rhinitis.

关 键 词：鼻内镜 蝶腭孔 变应性鼻炎 生存质量 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]