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作 者:马伟[1] 王世平[1] 何学东[1] 张俊[1] 张同钦[1] MA Wei;WANG Shiping;HE Xuedong;ZHANG Jun;ZHANG Tongqin(Department of Thoracic Surgery,Jianyang People's Hospital in Sichuan Province,Jianyang 641400,China)
机构地区:[1]四川省简阳市人民医院胸外科,四川简阳641400
出 处:《中国现代医生》2017年第30期50-53,共4页China Modern Doctor
摘 要:目的研究电视胸腔镜肺叶切除与传统开胸肺叶切除术的临床价值。方法将我院90例肺癌患者按随机数表法均分为观察组(电视胸腔镜肺叶切除术)和对照组(传统开胸肺叶切除术)。比较两组手术相关指标,分析手术前后心肺功能[用力肺活量(forced vital capacity,FVC)和第1秒呼吸率(forced expiraroty volume in one second,FEV1)]和炎症介质[白细胞(white blood cell,WBC)、C-反应蛋白(C-reactive protein,CRP)、白细胞介素-6(in terleukin-6,IL-6)],同时观察术后并发症。结果观察组切口长度、术中出血量、住院时间、拔管时间低于对照组,手术时间长于对照组(P<0.05)。观察组FVC、FEV1高于对照组,且术后6 min步行距离长于对照组(P<0.05)。观察组中WBC、CRP、IL-6低于对照组(P<0.05)。观察组术后并发症发生率低于对照组(P<0.05)。结论电视胸腔镜肺叶切除术治疗早期肺癌临床疗效更佳。Objective To sludy lhe clinical values of video-assisled ihoracoscopic lobeclomy and Iradilional ihoracic lobectomy. Methods 90 patients with lung cancer in our hospital were randomly divided into observation group (video- assisled lhoracoscopic lobedomy) and conlrol group (traditional thoracotomy lobectomy). The surgical related indicators between the two groups were compared. The cardiopulmonary function including forced vital capacity(FVC) and forced expiraroty volume in one second(FEVi) and inflammatory mediators including white blood cells(WBC), C-reactive protein(CRP) and interleukin-6 (IL-6) were analyzed before and after operation. The postoperative complications were ob-served at the same time. Results The length of incision,intraoperative blood loss,hospital stay and extubation time in the observation group were lower than those of the control group. The operation time in the observation group was longer than that of the control group(P〈0.05). The FVC and FEV| were higher in the observation group than those in the control group,and the walking distance was longer in the observation group than that of the control group(P〈0.05). WBC,CRP and It-6 in the observation group were lower than those in the control group(P〈0.05). The incidence of postoperative complications in the observation group was lower than that in the control group(P〈0.05). Conclusion Video-assisted thoracoscopic lobectomy is more effective in the treatment of early lung cancer.
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