多切面法联合彩色多普勒超声在胎儿先天性心脏病诊断中的应用  

Application of Multi Slice Combined with Color Doppler Ultrasonography in the Diagnosis of Fetal Congenital Heart Disease

作　　者：师晓娟[1] 张昕[1] 张鑫[1] 高洁[1] 段世玲[1] 

机构地区：[1]延安大学附属医院超声医学科,陕西延安716000

出　　处：《现代生物医学进展》2017年第31期6167-6169,6102,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨多切面法联合彩色多普勒超声在胎儿先天性心脏病(congenital heart diseases,CHD)诊断中的应用价值。方法:采用多切面法联合彩色多普勒超声对2015年5月~2016年7月300例胎儿进行CHD筛查,并与随访的产后超声或尸解结果作对照。结果:300例胎儿经产前超声联合多切面法检出CHD胎儿20例,检出率为6.7%,经产后超声或尸解确诊14例:三尖瓣下移畸形1例,室间隔完整型完全性大动脉转位1例,完全性房室间隔缺损1例,室间隔完整型肺动脉瓣闭锁1例,双流入型单心室1例,共同动脉干Ⅰ型2例,单纯室间隔缺损2例,法洛氏四联症2例,主动脉弓缩窄1例,肺动脉瓣轻度狭窄1例,二尖瓣闭锁并共同动脉干1例;误诊为单纯室间隔缺损1例,误诊为法洛氏四联症1例,病例流失4例。产前超声联合多切面法对有、无高危因素的检出率分别为3.79%、13.48%,比较有统计学意义(P<0.05)。产前超声联合多切面法诊断CHD的灵敏度为100%、特异度为99.66%、阳性预测值为80.00%、阴性预测值为100%。结论:多切面法联合彩色多普勒超声在胎儿CHD诊断中具有较高的应用价值。Objective： To explore the application value of Multi slice combined with color Doppler ultrasonography in the diagnosis of fetal congenital heart disease （congenital heart diseases, CHD）. Methods： 300 fetuses with CHD were detected by multi slice combined with color Doppler ultrasound to screen CHD, and the results were compared with those of postpartum ultrasound or autopsy. Results： 20 cases of CHD were detected with multi slice combined with color Doppler ultrasound in 300 fetuses, the detection rate was 6.7%, 14 cases were diagnosed by ultrasound or autopsy, including 1 case of Ebstein＇s anomaly, 1 case of complete transposition of the great arteries with intact ventricular septum,1 case of complete atrioventricular septal defect, I case of pulmonary atresia with intact ventricular septum, 1 case of double inlet type single ventricle, 2 cases of common truncus arteriosus type I, 2 cases of simple ventricular septal defect, 2 cases of tetralogy of failer,1 case ofcoarctation ofAorta, lcase of mild pulmonary stenosis and 1 case ofmitral atresia with common truncus arteriosus.1 case was diagnosised simple ventricular septal defect. Prenatal ultrasound combined with multi section method for the detection of high risk factors were respectively 3.79% and 13.48%（P 〈 0.05）. The sensitivity of prenatal ultrasound combined with multi section method in the diagnosis of CHD was 100%, the specificity was 99.66%, the positive predictive value was 80%, the negative predictive value was 100%. Conclusions： Multi slice combined with color Doppler ultrasound in the diagnosis of fetal CHD showed high value.

关 键 词：彩色多普勒超声 多切面 胎儿 先天性心脏病 

分 类 号：R541.1[医药卫生—心血管疾病] R445.1[医药卫生—内科学]