早产儿贫血影响因素分析  

Analysis of influence factors on anemia in preterm infants

作　　者：陈菲 田园[1] 龚小慧[1] 陈津津[1] 王瑜[1] 杨剑敏[1] 张宇鸣[1] 于广军[1] 

机构地区：[1]上海市儿童医院上海交通大学附属儿童医院,上海200062

出　　处：《临床儿科杂志》2017年第11期852-856,共5页Journal of Clinical Pediatrics

基　　金：上海市卫计委上海市第四轮加强公共卫生体系三年行动计划示范项目(No.GWIV-19);上海市申康医院发展中心项目(No.SHDC12014203)

摘　　要：目的分析早产儿在校正胎龄6月龄时发生贫血的影响因素。方法收集2014年6月至2015年11月门诊随访早产儿校正胎龄6月龄时的血红蛋白检测结果以及其他相关临床资料,分析影响早产儿贫血发生的相关因素。结果共入选早产儿124例,其中男70例、女54例,出生胎龄中位数33.7周,平均出生体质量(1 910±539)g。校正6月龄时38例发生贫血,贫血发生率为30.6%。贫血组和非贫血组的性别、出生胎龄、出生体质量差异均无统计学意义(P>0.05);两组在校正6月龄时的身长、体质量、头围差异也无统计学意义(P>0.05);两组喂养方式差异有统计学意义(P<0.001),其中贫血组的母乳喂养率较高为65.8%。在不同出生胎龄和不同出生体质量早产儿中,母乳喂养率的差异无统计学意义(P>0.05)。结论早产儿在校正胎龄6月龄时的贫血发生与母乳喂养有关,有必要对此进行进一步的分析和干预。Objective To study the influencing factors on anemia in preterm infants at the corrected age of 6-month-old based on gestational age （GA）, birth weight （BW） and feeding patterns. Method Preterm infants with GA〈37 weeks （n=124） were followed up to 6 months of corrected age （CA） between June 2014 and November 2015. The incidence of anemia in preterm infants among different groups according to GA, BW and feeding pattern was statistically analyzed. Results Preterm infants included are of 70 males and 54 females. Median age of GA was 33.7 weeks with an average BW of 1910g. The incidences of anemia was 30.6% （95% CI： 23%, 38%） in preterm infants at 6 months of CA, 66% in breast-fed preterm infants, which is significantly higher than 19% in those receiving mixed feeding and 13% in those receiving formula feeding （P=0.000）. No significant differences in anemia incidence were found among preterm infants of different GA and BW. Conclusions Anemia incidence in 6-month-old preterm infants is associated with feeding pattern, which conferrs greatest risk. It is necessary to undergo further analysis and treatments for preterm infants with anemia.

关 键 词：贫血 血红蛋白 胎龄 出生体质量 母乳喂养 早产儿 

分 类 号：R722.6[医药卫生—儿科]