猪瘟病毒基因型概述  

Genotypes of Classical Swine Fever Virus-A Review

作　　者：吴丹丹 彭忠[1] 陈焕春[1] 吴斌[1] 

机构地区：[1]华中农业大学动物医学院,农业微生物学国家重点实验室,生猪健康养殖协同创新中心,湖北武汉430070

出　　处：《动物医学进展》2017年第11期107-111,共5页Progress In Veterinary Medicine

基　　金：“十二五”国家科技支撑计划优良种猪高效利用关键工程化技术集成与示范(2014BAD20B00);“十二五”农村领域国家科技计划口蹄疫等重要家畜疫病防控净化技术集成研究与示范(2015BAD12B04)

摘　　要：猪瘟的发生和流行严重危害我国及世界养猪业的健康发展。由于猪瘟病毒(Classical swine fever virus,CSFV)只有一个血清型,所以基于传统的血清学方法针对临床上CSFV开展流行病学研究较为困难。随着分子生物学的发展,人们在对CSFV基因结构进行研究的过程中发现,基于其部分基因序列可以将该病毒分为若干基因型和基因亚型,进而揭示CSFV的区域分布和进化规律,有效地追踪CSFV的起源和传播特点。论文结合我国已有的CSFV流行病学数据,对现有的CSFV基因分型标准进行介绍,为进一步研究CSFV的变化规律、监测新型病毒出现,以及制定有效的防控净化措施提供参考。The outbreak and prevalence of classical swine fever （CSF） are the high-impact problems for global pig industry.More worrisome, relying on the traditional serological methodology to perform epidemic investigation on the causative agent of CSF,the classical swine fever virus （CSFV） ,is too difficult because CSFV displays only one serotype. However, with the development of molecular biology,it has been mentioned that CSFV could be divided into several genotypes based on some specific gene sequence harbored by the virus genome,and more helpful, the CSFV genotype could be regarded as a good indicator to monitor the virus evolution and transmission.In this review,we briefly summarized the current genotypes of CSFV,and also discussed the prevalent CSFV genotypes in China. Our aim is to provide some reference information for the further study of CSFV monitoring and even the CSFV prevention and control plan design.

关 键 词：猪瘟病毒 遗传进化分析 基因型 

分 类 号：S852.651[农业科学—基础兽医学]