常规超声及ABVS对乳腺结节病理结果对照研究  

Control Study of Conventional Ultrasound and ABVS with Breast Nodules Pathologic Results

作　　者：王惠[1] 靳凤梅 孙媛媛[1] 唐发兵[1] 马苏美[1] 

机构地区：[1]兰州大学第一医院超声科,兰州市730000

出　　处：《中国超声医学杂志》2017年第10期888-892,共5页Chinese Journal of Ultrasound in Medicine

基　　金：甘肃省自然科学基金(No.1606RJZA118)

摘　　要：目的探讨常规超声(US)联合自动乳腺全容积扫描(ABVS)技术对乳腺结节分类诊断的价值。方法回顾性分析104例(125个结节)经过US和ABVS检查的乳腺结节患者。以病理结果为金标准,分析US、US联合ABVS对乳腺结节BI-RADS分类的灵敏度、特异度、准确率和诊断价值。结果 US对125个结节BI-RADS分类诊断的灵敏度、特异度、准确率分别为94.2%、75.3%、83.2%;US+ABVS对125个结节BI-RADS分类诊断的灵敏度、特异度、准确率分别为96.2%、86.3%、90.4%;ROC曲线分析US、US联合ABVS对乳腺结节BI-RADS分类的曲线下面积(AUC)分别为0.948、0.979;分析US、US+ABVS对乳腺恶性结节BI-RADS分类与人乳腺球蛋白(hMAM)表达水平间存在正相关(r=0.573,P=0.000;r=0.645,P=0.000)。结论 US、US联合ABVS技术对乳腺结节具有较高的诊断价值,US、US联合ABVS对乳腺恶性结节BI-RADS分类与hMAM呈正相关,因此其可在一定程度上反映乳腺癌细胞的增殖性和侵袭力。Objective To explore the value of conventional ultrasound and automated breast volume scanner （ABVS） in classifying nodules of BI-RADS. Methods Totally 104 patients with 125 breast nodules who underwent both conventional ultrasound and ABVS were enrolled. The sensitivity, specificity, accuracy, diagnostic value of US and US＋ABVS were calculated to evaluate the BI-RADS classification of breast nodules taking the pathology as the gold standard. Results The sensitivity, specificity,accuracy of US for the 125 breast nodules were 94.2% ,75.3%, 83.2% ;The sensitivity,specificity,accuracy of US-l- ABVS for the 125 breast nodules were 96.2% ,86.3% ,90.4%. The area under curve （AUC） of BI-RADS classification based on US,US--ABVS were 0. 948,0. 979 ;There were posi- tive correlation between the BI-RADS classification of breast malignant nodules based on US, US＋ ABVS and the clas- sification of human mammaglobin （hMAM） （r=0. 573,P=0. 000;r=0. 645,P=0. 000）. Conclusions The diagnos- tic value of US, US＋ABVS of breast nodules were higher value. There were positive correlation between the BI- RADS classification of breast malignant nodules based on US, US--ABVS and the classification of hMAM, In a certain extent, US, US＋ ABVS of breast malignant nodules BI-RADS classification can reflects the proliferative and aggressive of breast cancer cells.

关 键 词：常规超声 自动乳腺容积扫描 乳腺结节 人乳腺球蛋白 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]