体感诱发电位联合视觉诱发电位在神经梅毒诊断中的应用  

Application of Somatosensory Evoked Potential Combined with Visual Evoked Potential in the Diagnosis of Neurosyphilis

作　　者：秦楠[1] 张雪青[2] 徐小林[3] 

机构地区：[1]天津医科大学,天津300000 [2]天津市环湖医院电生理科,天津300000 [3]天津市环湖医院神经内科,天津300000

出　　处：《医学新知》2017年第5期458-460,共3页New Medicine

摘　　要：目的 探讨体感诱发电位（somatosensory evoked potential,SEP）联合视觉诱发电位（visual evoked potential,VEP）在神经梅毒诊断中的应用.方法 选择2015年8月至2016年10月间的50例神经梅毒患者,包括25例有症状者（有症状组）和25例无症状者（无症状组）,另以25名无神经梅毒的普通人为对照组.分别进行SEP和VEP检查,并对检查结果进行组间对比分析.结果 有症状组和无症状组患者SEP检查的N20波潜伏期与对照组相比均有明显延长（P〈0.05）;有症状组和无症状组患者VEP检查的P100潜伏期与对照组相比均有明显延长（P〈0.05）.结论 SEP联合VEP检查有助于早期诊断神经梅毒,特别是可为无症状神经梅毒的诊断提供客观依据.Objective To explore the application of somatosensory evoked potential（SEP） combined with visual evoked potential（VEP） in the diagnosis of neurosyphilis. Methods 50 patients with neurosyphilis from 2015 to 2016 were selected,including 25 cases with symptoms （ symptomatic group） and 25 cases without symptoms （ asymptomatic group）. 25 ordinary people were selected as control group. All the cases were taken SEP and VEP. The results were compared. Results N20 potential time in SEP were longer in symptomatic group and asymptomatic group than that in control group（P 〈 0.05 ）. P100 potential time in VEP were longer in symptomatic group and asymptomatic group than that in control group （ P 〈 0.05 ）. Conclusion SEP combined with VEP can be helpful in early diagnosis of neu- rosyphilis and it can provide objective basis for diagnosis of asymptomatic neurosyphilis.

关 键 词：神经梅毒 体感诱发电位 视觉诱发电位 早期诊断 

分 类 号：R759.13[医药卫生—皮肤病学与性病学]