QuEChERS dSPE EMR-Lipid-LC-MS-MS测定鸡蛋中3种聚醚类抗球虫药物残留  

Determination of Three Kinds of Polyether Drug Residues in Eggs by QuEChERS dSPE EMR-Lipid-LC-MS-MS

作　　者：臧国栋 符靖雯 杨钦沾 黄子敬 陈孟君 

机构地区：[1]惠州市农产品质量安全监督检测中心,广东惠州516008

出　　处：《安徽农业科学》2017年第32期75-76,83,共3页Journal of Anhui Agricultural Sciences

基　　金：惠州市科技计划项目(20161117141959)

摘　　要：[目的]利用Agilent Bond Elut增强型脂质去除EMR-Lipid技术,建立了以QuEChERS dSP EEMR-Lipid为前处理测定鸡蛋中3种聚醚类药物残留的液相色谱-质谱联用(LC-MS-MS)方法。[方法]鸡蛋经酸化乙腈提取,Bond Elut EMR-Lipid QuEChERS净化,采用HPLC-MS-MS上机检测。[结果]3种聚醚类药物残留在2.0~100.0μg/L范围内与峰面积呈良好的线性关系(r>0.999),回收率在84.6%~107.0%。[结论]该方法前处理方便快捷、定量结果准确、再现性好,适用于鸡蛋中3种聚醚类药物残留的测定。[Objective]To establish a LC-MS-MS method for the determination of three kinds of polyether residues in eggs by QuEChERS dSPE EMR-Lipid as a pre-treatment using Agilent Bond Elut enhanced lipid removal EMR-Lipid technology. [Method]Egg was extracted by acidified acetonitrile,purified by Bond Elut EMR-Lipid Qu ECh ERS,and detected by HPLC-MS-MS.[Resul]There was a good linear relationship between the three kinds of polyether residues in the range of 2. 0-100. 0 μg/L,r > 0. 999. The recoveries ranged from 84. 6% to 107. 0%.[Conclusion]The method is convenient and accurate,and the quantitative results are accurate and reproducible. It is suitable for the determination of three kinds of polyether residues in eggs.

关 键 词：QUECHERS EMR-Lipid 液相色谱串联质谱 聚醚类 

分 类 号：S851.347[农业科学—预防兽医学]