温敏水凝胶释放润滑液的摩擦学性能  

Tribological Properties of the Lubricant Released by Temperature-Sensitive Hydrogel

作　　者：李月[1] 郭俊德[1] 董国忠[1] 董光能[1] LI Yue;GUO Junde;DONG Guozhong;DONG Guangneng(School of Mechanical Engineering, Xi＇an Jiaotong University, Xi＇an 710049, China)

机构地区：[1]西安交通大学机械工程学院,西安710049

出　　处：《西安交通大学学报》2017年第4期16-22,共7页Journal of Xi'an Jiaotong University

基　　金：国家自然科学基金资助项目(51475358)

摘　　要：为了改善人工关节的润滑性能、延长使用寿命,将温敏水凝胶作为载体释放人工关节润滑液,并通过磨损试验测试了释放液的摩擦学性能。采用开环聚合法制备了可在体温下实现溶胶-凝胶原位相变的聚己内酯-聚乙二醇-聚己内酯(PCEC)温敏水溶胶。将具有润滑作用的壳聚糖(CS)/牛血清白蛋白(BSA)混合液载入溶胶,在37℃相变为凝胶状态下进行体外释放试验。通过Bradford法测试了PCEC水凝胶释放润滑液的释放性能,通过磨损试验得到了释放液的摩擦学性能。试验结果表明:释放液中BSA的浓度为释放前凝胶的BSA浓度的1%左右;采用Al2O3陶瓷球与Co-Cr-Mo盘作为配副时,释放液的摩擦系数仅为蒸馏水、生理盐水或模拟体液摩擦系数的25%左右;释放液润滑下配副的磨损率比生理盐水低73%左右,比蒸馏水低50%左右,比模拟体液低20%左右。To improve the lubrication performance of artificial joint and to prolong its service life,temperature-sensitive hydrogel is taken as a carrier for releasing lubricants in artificial joint,and the tribological property of the released solution is investigated.The temperature-sensitive hydrogel of polycaprolactone-polyethylene glycol-polycaprolactone（PCEC） copolymer is synthesized by ring-opening polymerization method,and it can undergo the sol-gel transition at simulative body temperature.The release behavior of chitosan（CS）/BSA（bovine serum albumin）mixture carried by temperature-sensitive hydrogel is investigated by Bradford method in vitro.The tribological property of the release solution is measured by friction and wear tests.The concentration of BSA in the release solution is about 1% of the concentration of BSA before release.The friction coefficient of the release solution is about 25% of saline,distilled water or the simulation of body fluids.For Al_2O_3 ceramic ball and Co-Cr-Mo disc pair,the wear rate with the release solution is about 73%lower than that of the saline solution,about 50% lower than the distilled water and about 20%lower than the simulated body fluid.

关 键 词：人工关节 温敏水凝胶 摩擦学性能 体外释放 磨损率 

分 类 号：TH117[机械工程—机械设计及理论]