低管电压及低管电流颅脑容积CT灌注成像检查的可行性研究  

Feasibility study of low tube voltage and current on brain CT perfusion

作　　者：黄益龙[1] 韩丹[1] 蔡莉[1] 蒋悦[1] 王桂凤 李浚利 

机构地区：[1]昆明医科大学第一附属医院影像科,云南昆明650032

出　　处：《实用放射学杂志》2017年第11期1761-1764,共4页Journal of Practical Radiology

基　　金：基金项目：云南省创新团队基金资助项目（2014HC018）;昆明医科大学研究生创新基金资助项目（KM2007L33）.

摘　　要：目的 探讨80 kV低管电流颅脑容积CT灌注成像（CTP）的可行性。方法 60例颅脑CTP检查者，固定管电压80 kV，按照管电流分为A组（40 mAs），B组（60 mAs），C组（80 mAs），D组（100 mAs），E组（150 mAs）行头颅CTP检查，每组12例。分别比较5组尾状核头、额叶白质及颞叶白质灌注参数［脑血容量（CBV）、脑血流量（CBF）及平均时间（MTT）］、图像质量［主观评分、CT值、噪声（SD）、信噪比（SNR）、对比噪声比（CNR）值］及辐射剂量。结果 A、B组与E组尾状核头、额叶白质CBV、CBF组间比较差异有统计学意义（P＜0.05）;5组间图像质量客观指标比较，A^E组间CT值差异无统计学意义（P＞0.05）；A^D组SD较E组增高，而SNR均降低，仅A组CNR较E组降低有统计学意义（P＜0.05）。主观评分C、D组较E组评分差异无统计学意义（P〉0.05）。A^D组有效辐射剂量较E组均下降（P＜0.05）。结论 采用80 kV/80 mAs低剂量颅脑容积CTP检查，既保证灌注参数准确性及图像质量，又使辐射剂量降低46.22%（2.42 mSv）。Objective To investigate the feasibility of 80 kV and low tube current on brain CT perfusion（CTP）.Methods Sixty patients underwent 80 kV CTP examination, and were randomly divided into five groups according to different tube currents,A group （40 mAs）, B group （60 mAs）, C group （80 mAs ）, D group （100 mAs）, E group （150 mAs）. Twelve patients in each group were selected to analyze the parameters of the caudate nucleus and white matter frontals and temporal, including CBV, CBF and MTT. Subjective image quality, CT value： SD, SNR , CNR and radiation dose were measured and calculated in the 5 groups respectively. Results Differences of CBV and CBF in the caudate nucleus and white matter frontals were existed among A group,B group,and E group （P〈0.05）. There were no significant differences of CT value among the 5 groups （P〈0.05）. For the SD and SNR, E group was better than A--D groups （P〈0.05）. The CNR was higher in E group than that in A group （P〈0.05）.The subjective image quality score evaluation in C,D groups were not lower than that in E group（P〈0.05 ）.The ED of A--D groups were all lower than that of E group （P〈0.05）.Conclusion 80 kV/80 mAs brain CTP can obtain accurate perfusion parameter and satisfied image quality,and the radiation dose can be reduced by 46.22 %（2.42 mSv）.

关 键 词：头颅 CT灌注成像 低剂量 图像质量 

分 类 号：R814.42[医药卫生—影像医学与核医学] R816.1[医药卫生—放射医学]