妊娠合并胰腺炎临床特点40例分析  

Clinical study on 40 cases of pregnancy complicated with pancreatitis

作　　者：贺芳[1] 唐小林[1] 龚景进 苏春宏[1] 潘裕国[2] 陈敦金[1] 

机构地区：[1]广州医科大学附属第三医院妇产科重症孕产妇救治中心,广东广州510150 [2]广州医科大学附属第三医院外科,广东广州510150

出　　处：《中国实用妇科与产科杂志》2017年第11期1174-1177,共4页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的探讨妊娠合并急性胰腺炎(APIP)的病因与妊娠结局的关系。方法回顾性分析广州医科大学附属第三医院2003—2015年期间,分娩52 839例,其中40例APIP患者的临床资料。结果 APIP发生率0.08%。40例APIP患者中均无一例孕妇死亡。轻型胰腺炎16例(40.0%),中重症胰腺炎15例(37.5%),重症急性胰腺炎9例(22.5%)。胆源性急性胰腺炎为9例(22.5%),发生死胎1例;脂源性急性胰腺炎为9例(22.5%),发生死胎3例;1例(2.5%)同时合并脂源性、胆源性急性胰腺炎,孕34+5周胎膜早破顺产。余21例(52.5%)为特发性急性胰腺炎,发生死胎1例。结论 APIP发生率低但凶险,诊治过程中应尽早明确病因,多学科协作对因治疗,可明显改善母儿预后。Objective To explore pregnant outcomes by different causes of acute pancreatitis in pregnancy. Methods Forty patients who were diagnosed with APIP were retrospectively analyzed who were admitted to the Third Affiliated Hospital of Guangzhou Medical University from 2003 to 2015. The clinical records of the patients with APIP were reviewed for clinical features, laboratory examinations, and maternal and perinatal prognosis.Results Among the 40 patients, there were no maternal mortality, 16 cases of mild acute pancreatitis （40%）, 15 case of moderately severe acute pancreatitis （37.5%）and nine cases of severe acute pancreatitis （22.5%）. There was one case of stillbirth in 9 （22.5%） cases of biliary acute pancreatitis, and three cases of stillbirth in 9 （22.5%）cases of acute hyperlipidemic pancreatitis ; there was one case of stillbirth in 21 （52.5%）cases of idiopathic acute pancreatitis, and preterm delivery occurred in 1 （2.5%） mixed case because of premature rupture of membranes.Conclusion The incidence of APIP is low but it is associated with increased incidence of maternal and fetal mortality.Early diagnosis and multidisciplinary collaboration can significantly improve the maternal and fetal outcomes.

关 键 词：妊娠 胰腺炎 胆道结石 高脂血症 

分 类 号：R657.51[医药卫生—外科学]