补肾活血汤治疗PCOS排卵障碍性不孕的效果及对子宫动脉及卵巢间质动脉PI、RI的影响  

Effect of Using Bushen Huoxue Decoction in the Treatment of PCOS Induced Anovulatory Infertility and its Effect on PI and RI in Uterine and Ovarian Arteries

作　　者：曾倩[1] 张红霞[1] 王玉娜[1] 

机构地区：[1]沧州中西医结合医院东院区妇产科,河北沧州061000

出　　处：《四川中医》2017年第11期160-162,共3页Journal of Sichuan of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研项目(编号:2014354)

摘　　要：目的:观察补肾活血汤治疗多囊卵巢综合征(PCOS)排卵障碍性不孕的临床效果及其对子宫动脉及卵巢间质动脉PI、RI的影响。方法:选取确诊为PCOS排卵障碍性不孕的患者42例(均为肾虚血瘀型),并给予补肾活血汤加减进行治疗,1剂/d,30d为1个疗程,共服用3个疗程。以治疗前后自身对照的方法对患者排卵情况、妊娠情况、月经情况、子宫动脉及卵巢间质动脉血流情况进行分析。结果:42例患者中妊娠23例,妊娠率为54.76%;治疗周期共110个,有排卵的周期为75个,排卵率为68.18%;治疗后月经周期、经量及经期评分均优于治疗前,P<0.05;治疗后卵泡直径明显大于治疗前,P<0.05;治疗后子宫内膜及卵巢间质血流的PI和RI均明显降低,和治疗前比较,P<0.05。结论:对于PCOS排卵障碍性不孕患者,给予补肾活血汤治疗,能够提高排卵率,增强盆腔局部的血流状况,提高妊娠率。Objective ： To investigate the clinical effect of using Bushen Huoxue Decoction in the treatment of anovulatory in-fertility of polycystic ovary syndrome （PCOS） and its effect on P and R in uterine and ovarian arteries. Methods： 42patientswith PCOS diagnosed as anovulatory infertility were selected （they were both kidney deficiency and blood stasis type）, to giveModified Bushen Huoxue Decoction, lagent/d, 30d for lcourses. Before and after the treatment of patients with ovulation,pregnancy, menstruation, uterine artery and ovarian artery blood flow were analyzed. Results： In the 42patients, pregnancywas found in 23cases, and the pregnancy rate was about 54. 76% ; The treatment periods were 110, the ovulation cycles were75, the ovulation rate was about 68.18% ; After treatment, menstrual cycle, menstrual volume and menstrual score were betterthan before treatment, P〈0.05 ; After treatment, the follicular diameter was significantly larger than that before treatment, P〈0. 05 ; After treatment, the PI and RI of endometrial and ovarian stromal blood flow were significantly decreased, compared withbefore treatment, P〈 O. 05. Conclusion： For PCOS patients with ovulatory dysfunction infertility, to give Modified BushenHuoxue Decoction, can improve ovulation rate, enhance the local blood flow of pelvic cavity, improve pregnancy rate.

关 键 词：补肾活血汤 PCOS 排卵障碍 不孕症 

分 类 号：R271.14[医药卫生—中医妇科学]