芬太尼与瑞芬太尼静脉麻醉在老年普外科手术患者中的应用效果观察  

Effect of Intravenous Anesthesia With Fentanyl and Remifentanil in Elderly Patients Undergoing Department of General Surgery Surgery

作　　者：郭丽丽[1] 曹学照[1] 

机构地区：[1]中国医科大学附属第一医院麻醉科,辽宁沈阳110001

出　　处：《中国继续医学教育》2017年第24期75-77,共3页China Continuing Medical Education

摘　　要：目的探究芬太尼与瑞芬太尼静脉麻醉在老年普外科手术患者中的应用效果。方法选取我院收治的90例老年普外科手术患者,采取随机数字表法分为芬太尼组与瑞芬太尼组,每组各45例,对比两组围术期血流动力学指标。结果两组术后10 min与麻醉前相比SBP、DBP及HR升高,术后5 min与术中10 min相比SBP、DBP及HR降低,差异具有统计学意义(P<0.05)。芬太尼组术后5 min与麻醉前相比SBP、DBP及HR仍较高,差异无统计学意义(P>0.05)。芬太尼组术后5 min与瑞芬太尼组术后5 min相比SBP、DBP及HR均较高,差异具有统计学意义(P<0.05)。结论瑞芬太尼相比于芬太尼静脉麻醉应用于老年普外科手术患者中可获得更好的麻醉效果,血流动力学更加稳定,安全性更高。Objective To explore the application effect of fentanyl and remifentanil intravenous anesthesia in elderly patients with department of general surgery surgery. Methods 90 elderly patients in department of general surgery were randomly divided into fentanyl group and remifentanil group, with 45 cases in each group. The perioperative hemodynamic indexes of two groups were compared. Results SBP, DBP and HR increased in two groups at 10 min after operation compared with before anesthesia. Compared with 10 min after operation, SBP, DBP and HR decreased 5 min after operation, the diference was statistically signifcant （P 〈 0.05）. The SBP, DBP and HR of fentanyl group were higher than those before anesthesia 5 min after operation, and the diference was not statistically signifcant （P 〉 0.05）. the levels of SBP, DBP and HR at 5 min after operation in fentanyl group were higher than remifentanil group, the difference was statistically significant （P 〈 0.05）. Conclusion Compared to the anesthetic efect of remifentanil fentanyl intravenous anesthesia in elderly patients with Department of general surgery surgery can get better, more stable hemodynamics, higher safety.

关 键 词：芬太尼 瑞芬太尼 静脉麻醉 老年 普外科手术 

分 类 号：R614[医药卫生—麻醉学]