2010-2015年深圳市急性弛缓性麻痹病例流行特征分析  

Analysis of the epidemiological characteristics of acute flaccid paralysis cases in Shenzhen City between 2010 and 2015

作　　者：钟剑明[1] 邓凯杰[1] 周志峰[1] 段利娜[1] 许玉成[1] 董晨[1] 何宇衡 

机构地区：[1]深圳市福田区疾病预防控制中心,广东深圳518040

出　　处：《现代预防医学》2017年第22期4046-4049,4065,共5页Modern Preventive Medicine

基　　金：2015年深圳市福田区卫生公益性科研项目(FTWS2015047)

摘　　要：目的了解深圳市2010-2015年急性驰缓性麻痹病例流行病学特征,发现监测过程中存在问题,为维持无脊髓灰质炎状态提供依据。方法对2010-2015年深圳市福田区报告的AFP病例开展流行病学分析。结果 2010-2015年深圳市福田区共报告AFP病例206例,7例为疫苗相关株病毒病例;15岁以下儿童AFP报告发病率为1.61/10万~2.89/10万,病例报告最多月份为4月,以深圳市其他区为主(75.2%);深圳市儿童医院上报病例最多(91.7%),男女性别比为1.48∶1,病例以0~2岁年龄组为主(59.7%);报告症状最多是发热(52.4%),大部分病例有下肢乏力(90.8%);临床诊断前两位是乏力查因(63.6%)、格林巴利综合征(12.6%),60 d后随访有残留麻痹的有34人(16.5%)。结论 2010-2015年深圳市AFP监测未发现有野病毒株病例,需要继续加强医务人员培训,加大对市民健康教育,保持监测系统高质运行。Objective The study aimed to assess the epidemiological characteristics of acute flaccid paralysis （AFP） cases in Shenzhen City between 2010 and 2015, and find the problems in surveillance, so as to provide a reference for maintaining poliomyelitis free status. Methods Epidemiological analysis was performed on AFP cases reported in Futian District in Shenzhen between 2010 and 2015. Results A total of 206 AFP cases were reported in Futian District in Shenzhen City between 2010 and 2015, 7 cases were vaccine-associated strain virus cases. The incidence of AFP reported under the age of 15 were 1.61-2.89/100 000. Most cases were reported in April and in other districts of Shenzhen （75.2%）. Most cases were reported from Shenzhen Children＇s Hospital （91.7%）, and the male/female incidence ratio was 1.48：1. Most of the patients were at 0-2 age group （59.7%）. Fever （52.4%） was most frequently reported, and most cases complained about lower limb fatigue （90.8%）. The top two reasons for clinical diagnosis were fatigues （63.6%） and Guillain-Barre syndrome （12.6%）. At 60th day in followed-up, 34 cases still had residual paralysis （16.5%）. Conclusion There was not any wild virus case found in AFP surveillance in Shenzhen between 2010 and 2015, and the training of medical personnel should be strengthened, AFP monitoring did not find any case of wild virus strains, health education for the public should be increased to maintain the monitoring system running in high quality, it needs to continue to strengthen training of medical personnel, increase the public health education and maintain the high-quality running of the monitoring system.

关 键 词：急性驰缓性麻痹 脊髓灰质炎 流行特征 

分 类 号：R181.2[医药卫生—流行病学]