2型糖尿病合并下肢动脉病变患者的风险因素分析  

Analysis of risk Factors in Type 2 Diabetic Mellitus Patients with Lower Extremity Arterial Disease

作　　者：周祥群[1] 陈海金[1] 彭兴[1] 刘尚军 王芳[1] 韦迎娜[1] 

机构地区：[1]海南省第三人民医院,三亚572000

出　　处：《微循环学杂志》2017年第4期60-62,67,共4页Chinese Journal of Microcirculation

摘　　要：目的:回顾性对比分析2型糖尿病(T2DM)有无下肢动脉病变(LEAD)患者的临床资料、生活习惯和血糖血生化指标变化。方法:350例T2DM病患者,按照是否发生下肢动脉病变分为非LEAD组(n=165)和LEAD组(n=185),比较两组临床资料、生活习惯和血糖血生化指标水平的差异。结果:LEAD组高龄患者占69.19%、有糖尿病家族史者占47.57%、身体质量指数(BMI)>24者占38.92%、病程>10年者占63.24%、小学文化程度者占44.32%、合并高血压者占38.38%、合并冠心病者占42.70%、合并脑血管疾病者占35.68%,均显著高于非LEAD组(P<0.01),并且吸烟患者占31.89%、饮酒患者占34.32%均显著高于非LEAD组(P<0.01),而体育锻炼多的患者11.35%,营养膳食合理患者17.84%均显著低于非LEAD组(P<0.01);另外,LEAD组患者FPG、2hPG、LDL-C、TC、TG水平均显著高于非LEAD组(P<0.05),HDL-C则显著低于非LEAD组(P<0.05)。结论:T2DM患者发生下肢动脉病变相关危险因素有高龄、肥胖、合并症、不良生活习惯、高LDL-C、TG等,临床应加强重视。Objective： To analyze the clinical data, living habits, blood glucose and blood biochemical indexes in type 2 diabetes mellitus （T2DM） Patients with or without lower extremity arterial disease （LEAD）. Method： According to the occurrence of LEAD, 350 patients with T2DM disease were divided into non Lead group （n= 165） and group Lead （n= 185） . The clinical data, living habits, blood glucose and blood biochemical indexes were compared. Results： In the Lead group, the proportion of elderly patients（69. 19%）, pationts with family history of diabetes （47.57%） ,BMI〉24（38.92%）,davation 7 loyears（63.24%）,patients with a primary school education（44.32%）, potients with hypertersion （38.38%）, Patients with coronay heart disease （42.70 % ）. Patients with eerebrovascular disease（35.68%）, smokers（31.89 % ）, drinkers（34.32%） were signiticantly higher that of the nun bead group （P〈0.01） ,and patients who exercise mone（11. 35%） ,patients with reasonable nutritions diet（17.84%） were significontly lower than that of the nunglead group（P〈0.05）. Conclusion： Rehated factors of lead in patiats with T2DM include age,The peripheral artery disease and associated risk factors for type 2 diabetes patients, including age, obesity, complications, bad habits, LDL-C, TG, etc, should be strengthened clinical attention.

关 键 词：2型糖尿病 下肢动脉病变 危险因素 

分 类 号：R598.1[医药卫生—内科学] R587.1[医药卫生—临床医学]