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机构地区:[1]广州中医药大学,广东广州510405 [2]广州中医药大学针灸康复临床医学院华南针灸研究中心,广东广州510405
出 处:《中医药导报》2017年第20期62-66,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy
基 金:国家自然科学基金项目(81273845);广东省自然科学基金项目(9351040701000001)
摘 要:目的:对针灸治疗排卵障碍性不孕的有效性进行Meta分析。方法:通过计算机检索中国期刊全文数据库(CNKI)、万方数据资源系统、中国生物医学文献光盘数据库(CBM)、Pub Med及Web of Science数据库1999年1月至2016年7月所有针灸治疗排卵障碍性不孕的随机对照临床试验文献。依据Cochrane协作网编写的质量评价标准Risk of bias table对纳入文献进行偏倚风险和质量评估,对针灸治疗排卵障碍性不孕的妊娠率、排卵率、流产率进行Meta分析,Revman5.2软件进行异质性检验,并根据异质性检验结果采用固定或随机效应模型合并OR值,P值及95%CI。结果:针灸治疗排卵障碍性不孕的妊娠率明显高于对照组[OR=2.56,95%CI(1.94,3.38),P<0.000,01];针灸+中药组妊娠率明显高于西药组[OR=3.24,95%CI(2.19,4.77),P<0.000,01]。结论:针灸治疗排卵障碍性不孕的疗效优于西药,针灸治疗的同时辅以中药疗效更佳。Objective: To evaluate the clinical effects of acupuncture on anovulation infertility using metaanalysis method.Methods: Literature analysis was established based on the collection of the RCT(randomizedcontrolled trials) clinical research literatures about the treatment of anovulation infertility with acupuncture by searching China journal full text database(CNKI),Wanfang database,Chinese biomedical literature CD-ROM Database(CBM),Pubmed and Web of Science database from January 1999 to July 2016.The test bias risk and quality assessment in accordance with Risk of bias table made by Cochrane network,Rev Man5.2 was used for heterogeneity test and according to the results determine if a fixed or a random effect model,then getting the pooled OR,P value and the 95% confidence interval.Results: The successful pregnant rate of acupuncture group significantly higher than western medicine group [OR =2.56,95% CI(1.94,3.38),P〈 0.000,01].The successful pregnant rate of the combination of acupuncture and Chinese medicine group significantly higher than western medicine group [OR=3.24,95% CI(2.19,4.77),P〈0.000,01].Conclusion: Acupuncture is an effective method for anovulation infertility than western medicine and acupuncture added with traditional Chinese medicine is better.
关 键 词:针灸 排卵障碍性不孕 META分析 随机对照试验
分 类 号:R271.14[医药卫生—中医妇科学]
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