用UPLC法测定银黄含片中8种活性成分含量的效果研究  

Determination of eight components in Yinhuang buccal tablets by UPLC

作　　者：于海波 

机构地区：[1]徐州市食品药品监督检验中心,江苏徐州221006

出　　处：《当代医药论丛》2017年第19期173-175,共3页

基　　金：徐州市科技计划项目(XF11C039)

摘　　要：目的 :研究用UPLC法测定银黄含片中8种活性成分含量的效果,以期为该药的质量控制研究提供参考依据。方法 :采用UPLC法对银黄含片中绿原酸、咖啡酸、木犀草苷、黄芩苷、木犀草素、汉黄芩苷、黄芩素、汉黄芩素的含量进行测定。结果 :银黄含片中8种活性成分的线性关系良好,相关系数均>0.9997,加样回收率均在97.3%~102.0%之间,RSD均小于1.2%。结论 :用UPLC法测定银黄含片中8种活性成分含量的效果好。可采用该方法对银黄含片进行全面、有效的质量控制。Objective To study determination of eight active constituents in Yinhuang buccal tablets by UPLC. Methods To determine contents of chlorogenic, caffeic acid, galuteolin, baicalin, luteolin,wogonoside, baicalein,wogonin in Yinhuang buccal with UPLC. Results The 8 active constituents in Yinhuang are on good terms, correlation coefficient are all less than 0.9997, average recovery are all between 97.3% ~ 102.0%,RSD are all lower than 1.2%. Conclusion The effect of determinate active constituents with UPLC is good, and we can control quality of Yinhuang buccal tablets with UPLC,.

关 键 词：超高效液相 银黄含片 活性成分 含量测定 

分 类 号：R284.1[医药卫生—中药学]