NLRP9b： a novel RNA-sensing inflammasome complex  

作　　者：Chinh Ngo Si Ming Man 

机构地区：[1]Department of Immunology and InfectiousDisease, The John Curtin School of MedicalResearch, Australian National University, Can-berra, 2601, Australia

出　　处：《Cell Research》2017年第11期1302-1303,共2页细胞研究（英文版）

摘　　要：Inflammasome sensors recognize pathogens and danger signals and assemble an immune signaling com- plex, which induces the secretion of pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis. A new study published in Nature now de- scribes a new inflammasome sensor NLRP9b in intestinal epithelial cells, which in concert with the RNA sensor DHX9, recognize short dsRNA from Rotavirus.

分 类 号：Q[生物学]