镉中毒与金属硫蛋白表达的研究进展  

Advancements in cadmium intoxication and metallothionein expression

作　　者：胡曦尹 冯扬[1] 李岩 

机构地区：[1]遵义医学院公共卫生学院,贵州遵义563099

出　　处：《职业与健康》2017年第21期3022-3024,F0003,共4页Occupation and Health

基　　金：基金项目:遵义科技局公共卫生与预防医学科技创新人才团队(E-144)

摘　　要：镉(Cd)是自然环境中的一种重金属元素,随着人类进行矿石开采及金属冶炼等作业增加以及近年来工厂排污不规范,导致Cd污染发生的概率明显增高。Cd能导致肝、肾、骨骼、肺及听力的损伤,甚至引发癌症的发生。金属硫蛋白能与金属Cd相结合减弱Cd对机体脏器的毒性。因此了解金属硫蛋白在不同类型Cd中毒的表达具有重要意义。Cadmium is an environmental heavy metal element. With the increase of mining and smelting, and the unstandardized discharging of factory sewage in recent years, the cadmium pollution is significantly increasing. Cadmium may cause the damage of liver, kidney, bone,lung and hearing, even lead to cancer. The binding of metallothionein and cadmium can reduce the toxicity of cadmium to the organs. Therefore, to understand the expressionof metallothionein in different cadmium intoxication has impor- tant implications.

关 键 词：镉 金属硫蛋白 急性镉中毒 慢性镉中毒 

分 类 号：R181.3[医药卫生—流行病学]