TP-CMIA法与TP-ELISA法检测献血者梅毒螺旋体特异性抗体的效果比较  

Comparison of TP-CMIA and TP-ELISA in detecting the specific antibody of Treponema pallidum in blood donors

作　　者：祝宇姝 

机构地区：[1]商丘市第一人民医院检验科,河南商丘476100

出　　处：《实用妇科内分泌电子杂志》2017年第24期11-12,共2页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的比较化学发光法(TP-CMIA)与酶联免疫吸附法(TP-ELISA)检测献血者梅毒螺旋体特异性抗体的效果。方法选择本院收到的无偿献血血液样本51454份,均施以TP-CMIA法与TP-ELISA法检测其梅毒螺旋体特异性抗体,对比不同检测方法对梅毒螺旋特意抗体的阳性检出率。结果使用TP-CMIA阳性检出率高于TP-ELISA,差异有统计学意义(P<0.05)。结论献血者梅毒螺旋特异性抗体检测使用TPCMIA法检测的敏感度较TP-ELISA法好,具有检测快、操作简单、自动化等优势,在医院血液梅毒螺旋特异性抗体的检测中应用价值高。Objective To compare the effect of chemiluminescence（TP-CMIA） and enzyme-linked immunosorbent assay（TP-ELISA） on detection of Helicobacter pylori-specific antibodies in blood donors. Methods 51454 samples of blood samples received from our hospital were selected and tested with TP-CMIA and TP-ELISA to detect the specific antibody of Treponema pallidum. The positive detection rate of syphilis spiral specific antibody was compared with different detection methods. Results The positive rate of TP-CMIA was higher than TP-ELISA, the difference was statistically significant（P〈0.05）. Conclusion The sensitivity of detection of TPCMIA is better than that of TP-ELISA, and it has the advantages of rapid detection, simple operation and automation. It has high application value in the detection of blood syphilis spiral specific antibody in hospital The

关 键 词：梅毒 螺旋体特异性抗体 献血者 TP-CMIA法 TP-ELISA法 

分 类 号：R446.6[医药卫生—诊断学] R759.1[医药卫生—临床医学]