亚甲蓝联合罗哌卡因用于肛门病术后镇痛的临床观察  

Clinical Observation on the Anagesia of Methylene Blue Combined with Ropivacaine after Anal Disease Surgery

作　　者：王猛[1] 蒋进广[1] 陈娟[1] 张欣 WANG Meng;J IANG Jin-guang;CHEN Juan;ZHANG Xin(Suqian City＇s Hospital of TCNl,Suqian ,diangsu 22380)

机构地区：[1]江苏省宿迁市中医院,江苏宿迁223800

出　　处：《中国肛肠病杂志》2017年第9期56-58,共3页Chinese Journal of Coloproctology

摘　　要：为了观察亚甲蓝联合罗哌卡因用于肛门疾病术后患者镇痛的疗效，将2016年1月至2017年1月江苏省宿迁市中医院肛肠科120例住院患者，参照随机数字表法分为观察组和对照组，每组各60例。观察组患者术后在创口周围多点注射亚甲蓝合罗哌卡因，对照组给予口服洛索洛芬钠分散片。分别记录2组患者术后12h、24h、48h及7d的疼痛情况，疼痛程度评分采用视觉模拟评分法（VAs）进行评分。并观察用药期间2组患者有无出现明显药物不良反应。结果显示，观察组患者在术后12h、24h、48h及7d的VAS评分均明显小于对照组，差异均有统计学意义（P〈0．05），且2组患者均未出现明显药物不良反应。结果表明，亚甲蓝联合罗哌卡因对肛门病术后镇痛效果显著，且无明显药物不良反应，是肛门病术后有效、安全的镇痛方法。This study was to observe the analgesia efficacy of Methylene blue combined with Ropivacaine after surgery for anal diseases,randomly divided 120 patients who admitted in authors＇ hospital coloprocto- logical department from Jan. 2016 to Jan. 2017 into observation group and control one, 60 cases for each, which the former received multi-point injection of Methylene blue plus Ropivacaine around wound after surgery,meanwhile the latter orally administered Loxoprofen sodium disperisible tablets; then recorded both groups＇ pain condition at the 12th,24th,48th hrs and on the 7th day after surgery as well as with or without significant adverse reaction to drugs,and took rating on pain degree by using VAS method.As results,in above all time-points VAS ratings of the former were significantly lower than that of the latter, there was statistical difference（ P 〈0.05） ,there was no distinct adverse reaction to drugs in both groups. Results show that the combination medication has great analgesia efficacy, and no significant drug＇s adverse reaction,thus is a safe and effective analgesia method for anal disease after surgery.

关 键 词：肛门疾病 术后 镇痛 亚甲蓝 罗哌卡因 洛索洛芬钠分散片 

分 类 号：R971.2[医药卫生—药品]