2006-2014年德清县农村成人2型糖尿病患病情况及流行趋势  

Prevalence and change of type 2 diabetes mellitus among rural adults in Deqing County,Zhejiang Province in China during 2006-2014

作　　者：陈晓英[1] 吴照帆 王学才[2] Chen Yue 董晓莲[2] 朱建福[2] 肖甜[1] 姜庆五[1] 付朝伟[1] Chen Xiaoying;Wu Zhaofan;Wang Xuecai;Chen Yue;Dong Xiaolian;Zhu Jianfu;Xiao Tian;Jiang Qingwu;Fu Chaowei(Department of Epidemiology, School of Public Health, and Key Laboratory of Public Health Safety, Fudan University, Shanghai 200032, Chin)

机构地区：[1]复旦大学公共卫生学院流行病学教研室公共卫生安全教育部重点实验室,上海200032 [2]浙江省德清县疾病预防控制中心 [3]加拿大渥太华大学医学院

出　　处：《卫生研究》2017年第6期868-874,887,共8页Journal of Hygiene Research

基　　金：国家自然科学基金(No.81473038);上海市公共卫生重点学科建设计划(No.15GWZK0801)

摘　　要：目的了解2006—2014年浙江省德清县农村成人2型糖尿病(type 2diabetes mellitus,T2DM)患病现状及变化趋势,并探索其患病的影响因素。方法随机整群抽取浙江省德清县8个农村社区,以18周岁及以上户籍居民为研究对象,于2006—2008年、2011—2012年和2013—2014年分三阶段完成横断面调查,其中2006—2008年实际调查6562人,2011—2012年11 763人,2013—2014年10 904人。调查对象接受问卷调查(包括人口学、生活方式及疾病史信息)、体格检查(身高、体重、血压等)和空腹血糖测量。T2DM诊断标准为空腹血糖≥7.0 mmol/L或自报患有医生诊断的糖尿病或正在接受糖尿病治疗。结果 2006—2014年德清县农村成人T2DM及空腹血糖受损(impaired fasting glucose,IFG)患病率均呈逐年上升趋势,T2DM标化患病率依次为1.2%、1.6%和2.1%,IFG患病率分别为7.2%、18.7%和22.8%。多因素Logistic回归分析显示,高年龄(与18~39.9岁相比:调整OR(aOR)_(40-59.9岁)=5.20,95%CI 2.74~9.89;aOR_(60岁及以上)=8.02,95%CI 4.19~15.35)、女性(aOR=1.23,95%CI 1.02~1.49)、糖尿病家族史(aOR=4.86,95%CI3.49~6.77)、超重/肥胖(aOR_(超重)=1.88,95%CI 1.61~2.20;aOR_(肥胖)=5.10,95%CI 4.06~6.41)、高血压(aOR=2.84,95%CI 2.44~3.31)、荤食(与饮食荤素均衡相比:aOR=2.25,95%CI 1.89~2.69)是T2DM的独立危险因素,而饮茶(aOR_(饮茶)=0.81,95%CI 0.68~0.95)是其保护因素。结论 T2DM在德清县农村成人中流行水平较低,但呈快速上升趋势;高年龄、女性、家族史、超重/肥胖、荤食和高血压等是T2DM患病的危险因素,饮茶是保护因素。Objective To describe the prevalence of type 2 diabetes mellitus （T2DM） in rural Deqing County, Zhejiang Province, and explore its risk factors. Methods Random cluster sampling was used to select 8 rural communities in Deqing County, Zhejiang Province, and a cross-sectional survey was conducted in 2006 -2008, 2011 -2012 and 2013 -2014, respectively. Totally, 6562 eligible subjects were investigated in 2006 -2008, 11 763 eligible subjects in 2011 -2012, and 10 904 eligible subjects in 2013 -2014. Data on demography, life style and disease history, and physical examination such as height, weight and blood pressure were collected. Also, fasting plasma glucose was tested. T2DM was defined as who having fasting plasma glucose ≥7.0 mmol/L or was diagnosed by doctors or receiving diabetic treatment. Results In 2006 - 2008, 2011 -2012 and 2013 -2014, the standardized prevalences of T2DM were 1.2% 1.6% and 2.1% and those of impaired fasting glucose （IFG） were 7.2% ,18.7% and 22. 8% , respectively. There were increasing trends over years for both. After adjustment for other covariates in logistic regression, age （compared with age between 18 to 39.9 years old： aOR40-59.9 =5.20, 95% CI2.74 -9.89; aOR6o_ =8.02, 95% CI4.19 - 15.35）, female （aOR=l.23, 95% CI1.02-1.49）, family history ofT2DM （aOR= 4.86, 95% CI 3.49 - 6.77） , overweight/obesity （overweight： aOR = 1.88, 95% CI 1.61 - 2.20 ; obesity ： aOR = 5.10, 95% CI 4.06 - 6.41 ）, hypertension （ aOR = 2.84, 95%CI2.44-3.31）, having meat mainly （aOR=2.25, 95%CI1. 89-2.69） and tea drinking （aOR = 0.81, 95% CI 0. 68 -0.95 ） were significantly correlated with T2DM. Conclusion The prevalence of T2DM increased over time in rural Deqing County, China. Age, gender, family history of T2DM, overweight or obesity, hypertension, diet and drinking tea were significantly related to T2DM.

关 键 词：2型糖尿病 患病率 影响因素 农村成人 流行病 

分 类 号：R587.1[医药卫生—内分泌] R181.37[医药卫生—内科学]