双密度分离法提取化妆品中的聚乙烯微珠  

Isolation of polyethylene microbeads in cosmetics by double-density separation

作　　者：屈沙沙 朱会卷[1] 刘锋平[1] 董晓杰[1] 朱英[1] Qu Shasha;Zhu Huijuan;Liu Fengping;Dong Xiaojie;Zhu Ying(National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China)

机构地区：[1]中国疾病预防控制中心环境与健康相关产品安全所,北京100021

出　　处：《卫生研究》2017年第6期986-990,共5页Journal of Hygiene Research

基　　金：中国疾病预防控制中心环境与健康相关产品安全所重大项目(No.16zdxm06)

摘　　要：目的建立一种从含有磨砂成分的化妆品中稳定分离、测定聚乙烯微珠的方法并观察其形状和粒径。方法利用聚乙烯与两种分散溶液(氯化钠溶液和乙腈)的相对密度差异,分离化妆品中的聚乙烯微珠,重量法测定其含量,采用显微镜观察其形态及粒径。结果化妆品中聚乙烯微珠的加标回收率为93.2%~98.2%,相对标准偏差(RSD)0.16%~2.81%。标签上标明含有微珠的14种市售样品中均能分离出聚乙烯微珠,含量为0.11%~7.76%,粒径范围100~200μm,形状基本规则,颜色主要为蓝色和白色。结论该方法稳定、简便,可以满足密度小于1 g/cm^3的聚乙烯微珠的分离。Objective To develop a stable method for isolation and quantitation of polyethylene microbeads in cosmetics and to observe its morphology and size. Methods Polyethylene microbeads were isolated by using the difference of relative density between polyethylene and two kinds of separation solutions （sodium chloride solution and acetonitrile）. The contents of polyethylene microbeads in cosmetics were determined by gravimetric method. The morphology and particle size were observed by microscope. Results A stable method was developed by optimizing experimental method. The recoveries were from 93.2% to 98.2% , and the relative standard deviations varied in the range from 0. 16% to 2.81%. Samples labeled containing microbeads could be isolated polyethylene microbeads, and the contents were from 0.11% to 7.76% , and size ranged from 100 μm to 200 μm. The morphology of isolated polyethylene microbeads were mostly regular, and color were mainly blue and white. Conclusion The developed method is simple, repeatable and reliable that can be used for isolation and quantitation of polyethylene microbeads with a density lower than 1 g/cm in cosmetics.

关 键 词：聚乙烯微珠 双密度分离 化妆品 

分 类 号：TQ658[化学工程—精细化工] R168[医药卫生—公共卫生与预防医学]