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机构地区:[1]宝鸡市人民医院呼吸内二科,陕西宝鸡721000
出 处:《西北国防医学杂志》2017年第10期677-681,共5页Medical Journal of National Defending Forces in Northwest China
摘 要:目的:观察不插管全麻下经支气管镜高频电刀结合冷冻疗法治疗气管内新生物的效果和安全性。方法:选取2013-03~2017-03在我院诊断为气管内新生物如肿瘤、炎性肉芽肿或息肉、平滑肌瘤,并接受不插管全麻下纤维支气管镜高频电刀结合冷冻疗法治疗的66例患者为研究对象。所有患者均在丙泊酚、芬太尼和维库溴铵静脉麻醉的条件下进行手术。术中监测患者的心率、血压、呼吸、血氧饱和度等生命体征,术后将患者的气道阻塞情况、肺功能、气促分级、Karnofsky评分(KPS)与治疗前进行比较,从而评估此种治疗方法的疗效和安全性。结果:术中患者各项生命体征平稳,术后患者的气道阻塞情况、肺功能、气促分级、KPS评分均有明显改善,且术中、术后未见明显并发症。结论:不插管全麻下经支气管镜高频电刀结合冷冻疗法治疗气管内新生物能明显改善患者的气道阻塞、缓解呼吸困难,术中患者的耐受性较好,是一种安全有效的治疗气管内新生物的方法。Objective: To observe the effects and security of bronchoscope endotherm knife combined with cryotherapy under non- intubation anesthesia in treatment of neoplasm in trachea.Methods: Sixty- six patients who were diagnosed as neoplasm in trachea such as tumor,inflammatory granuloma or polypliomyoma and received bronchoscope endotherm knife combined cryotherapy under non--intubation anesthesia as research objects from March 2013 to March 2017.All the patients received operation under non--intubation anesthesia,that is to say using propofol, fentanyl and vecuronium bromide to conduct the intravenous anesthesia and operation.The heart rate, blood pressure,breath, oxyhemoglobin saturation and other life signs were monitored. The airway obstruction situation, pulmonary function, shortness of breath classification and Karnofsky score(KPS) between before and after operation were compared. The clinical effects of this therapy method was evaluated.Results:All the life signs of patientswere stable during the operation. The airway obstruction situation, pulmonary function, shortness of breath classification and KPS of the patients were improved after the operation.No complications were observed during and after the operation. Cone|usion: Bronchoscope endotherm knife combined cryotherapy under non--intubation anesthesia can improve the airway obstruction situation and alleviate expiratory dyspnea, patients have well tolerance during the operation,this method can be a safe and effective therapy to treat the neoplasm in trachea.
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