谷维素在糖尿病神经病变中的应用研究进展  

Research progress of oryzanol in diabetic neuropathy

作　　者：孙新娟[1] 陈金安 张洁[1] 胡志为 王雷[1] 王爱萍[1] SUN Xin-Juan;CHEN Jin-An;ZHANG Jie;HU Zhi-Wei;WANG Lei;WANG Ai-Ping(The 454th Hospital of PLA, Nanjing 210000, China)

机构地区：[1]中国人民解放军第四五四医院,江苏南京210000

出　　处：《转化医学电子杂志》2017年第11期65-68,共4页E-Journal of Translational Medicine

基　　金：2014军区重大课题(10Z14)

摘　　要：糖尿病神经病变是糖尿病最常见、最复杂的慢性并发症之一,是造成糖尿病患者反复住院的主要原因.对糖尿病周围神经病变的治疗除积极控制血糖外,临床采用多种治疗方法改善患者的四肢感觉异常,缓解足部疼痛等.谷维素主要用于治疗植物神经功能失调,临床上也用于治疗糖尿病周围神经病变.本文对糖尿病神经病变的发病机制进行综述,并探讨谷维素在糖尿病神经病变中的应用前景,为糖尿病神经病变的临床治疗提供方向.Diabetic neuropathy is one of the most common and most complicated chronic complications of diabetes,and is the main cause of repeated hospitalization in diabetic patients. Besides control of blood sugar,variety of treatment methods are adopted to improve acroparesthesia of patients,relieve foot pain and so on.Oryzanol is mainly used to treat autonomic dysfunction,and also used to treat diabetic peripheral neuropathy. In this paper,the pathogenesis of diabetic neuropathy is reviewed,and the application prospect of oryzanol in diabetic neuropathy is discussed,which provides direction for treating diabetic neuropathy.

关 键 词：糖尿病神经病变 谷维素 机制 

分 类 号：R587.1[医药卫生—内分泌]