排毒保肾丸对腹膜透析营养不良的影响  

Effect of Paidu Baoshen Pill on Peritoneal Dialysis Malnutrition

作　　者：徐媖 陈帮明 刘干炎 刘永芳 熊清玓 王金象 林雪菲 柯永芳 

机构地区：[1]九江市中医医院肾病科,江西九江332000

出　　处：《中国中医药现代远程教育》2017年第19期84-86,共3页Chinese Medicine Modern Distance Education of China

基　　金：江西省卫生计生委中医药科研项目【No.2015A183】

摘　　要：目的观察排毒保肾丸(大黄虫丸加减)治疗腹膜透析(PD)营养不良的疗效。方法将符合研究要求的连续性不卧床腹膜透析(CAPD)患者80例随机分为治疗组和对照组,每组各40例。在基础治疗的同时,治疗组予排毒保肾丸3 g,每日2次,对照组予复方酮酸片0.12 g·kg^(-1)·d^(-1)。治疗6个月,观察2组患者治疗前后体重指数(BMI)、中臂肌围(MAMC)、上臂肌围(AMC)、主观综合营养评估(改良法SGA)、血清前白蛋白(PA)、白蛋白(Alb)、肌酐(Scr)和尿素氮(BUN)的变化。结果与本组治疗前比较,治疗组和对照组BMI、MAMC、AMC、ALB、PA均升高(P<0.05或P<0.01),SGA、Scr和BUN降低(P<0.01或P<0.05);与对照组治疗后比较,治疗组SGA和Scr降低(P<0.05)。结论排毒保肾丸能提高CAPD患者BMI、MAMC、AMC、ALB、PA,降低Scr、BUN和SGA评分,具有改善营养不良的作用。Objective To observe the effect of Paidu Baoshen pill（ modified Dhuang Zhechong pills） in peritoneal dialysis malnutrition patients. Methods 80 cases of peritoneal dialysis malnutrition patients were randomly divided into treatment group and control group, with 40 cases in each group. On the basis of conventional therapy, the treatment group and control group were given Paidu Baoshen pill and compound keto acid tablets respectively for 6 months. Then the change of body mass index（BMI）, middle arm circumference（ MAMC）, arm muscle circumference（ AMC）, subjective comprehensive nutritional assessment（ modified SGA）, serum prealbumin（PA）, albumin（Alb）, creatinine（Scr） and urea nitrogen（BUN） were observed. Results Comparing with before treatment, the BMI, MAMC, AMC, ALB and PA increased（ P〈0.05 or P〈0.01） in the two groups, but the SGA, Scr and BUN decreased（ P〈0.01 or P〈0.05）. In comparison with the control group after treatment, the SGA and Scr decreased in the treatment group（ P〈0.05）. Conclusion Paidu Baoshen pill can increase the BMI, MAMC, AMC, ALB and PA, reduce Scr, BUN and SGA score, and improve the peritoneal dialysis malnutrition.

关 键 词：大黄虫丸 腹膜透析 营养不良 水肿 虚劳 

分 类 号：R277.5[医药卫生—中医学]