离子液体表面活性剂的合成与应用(Ⅺ)——与生物活性分子的相互作用  

Synthesis and application of ionic liquid surfactants(Ⅺ) Interactions between bioactive molecules

作　　者：吴磊[1] 杨许召[1] 邹文苑[1] 徐清杰[1] 王军[1] 

机构地区：[1]郑州轻工业学院,河南郑州450002

出　　处：《日用化学工业》2017年第11期607-611,620,共6页China Surfactant Detergent & Cosmetics

基　　金："十二五"国家科技支撑计划资助项目(2013BAC01B04);国家自然科学基金资助项目(21176228);河南省科技攻关项目(162102210056);郑州市科技攻关项目(141PQYJS555)

摘　　要：从3方面综述了离子液体表面活性剂与生物活性分子的相互作用。亲油性的离子液体表面活性剂可与β-环糊精形成1:1,1:2或2:1型包合物,而亲水性的离子液体表面活性剂不能与β-环糊精形成包合物,这些包合物的形成影响了表面活性剂的cmc和在界面的吸附。离子液体表面活性剂能够与牛血清蛋白、β-酪蛋白、溶菌酶等蛋白质相互作用,影响蛋白质的分子构型以及在油/水界面的吸附状态。离子液体表面活性剂与DNA的相互作用主要来源于静电吸引和疏水作用。Interactions between ionic liquid surfactants and bioactive molecules were summarized in three aspects. Hydrophobic ionic liquid surfactants can form inclusion complexes with β-cyclodextrin（ β-CD）according to ratio of 1： 1,1： 2 or 2： 1;while hydrophilic ionic liquid surfactants cannot. The cmc and adsorption of ionic liquid surfactants at interface are affected by the inclusion complexes. The molecular structure and adsorption of protein at the interface between water and oil are affected by the interaction of ionic liquid surfactants with varied kinds of protein,such as bovine serum albumin,β-casein and lysozyme. The interactions between ionic liquid surfactants and DNA are caused by electrostatic attraction and hydrophobic action.

关 键 词：表面活性剂 离子液体 环糊精 蛋白质 脱氧核糖核酸 

分 类 号：TQ423[化学工程]