人工颈椎间盘置换和椎体间融合治疗颈椎病的临床疗效  

Clinical efficacy of artificial cervical disc replacement and cervical interbody fusion in treatment of cervical spondylosis

作　　者：陈海峰[1] 王鹏[1] 马荣[1] 

机构地区：[1]南通大学附属建湖医院骨科,江苏省建湖县224700

出　　处：《江苏医药》2017年第21期1529-1531,共3页Jiangsu Medical Journal

摘　　要：目的观察人工颈椎间盘置换和椎体间融合治疗颈椎病的临床疗效。方法将40例颈椎病患者随机均分为人工颈椎间盘置换组(A组)和椎体间融合组(B组),比较两组临床治疗效果。结果两组治疗后日本骨科协会(JOA)和世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评分均较治疗前提高(P<0.05或P<0.01)。与B组相比,A组治疗优良率高(90.0%vs.60.0%),并发症发生率低(5.0%vs.35.0%)(P<0.05);B组治疗后关节活动度(ROM)评分较治疗前降低(P<0.05);A组治疗后WHOQOL-BREF和ROM评分高于B组(P<0.05或P<0.01)。结论采用人工颈椎间盘置换治疗颈椎病安全、有效。Objective To observe the clinical efficacy of artificial cervical disc replacement and cervical interbody fusion in the treatment of cervical spondylosis .Methods Forty patients with cervical spondylosis were equally randomized into two groups of A （operated by artificial cervical disc replacement） and B （operated by cervical interbody fusion ） .The clinical outcomes were compared between two groups .Results The scores of Japanese Orthopaedic Association （JOA ） and WHO quality of life-BREF（WHOQOL-BREF） after treatment were higher than those before treatment in both groups（P〈0 .05 or P＆lt;0 .01） .Compared with group B ,the patients in group A had higher excellent and good rate（90.0% vs .60.0% ） and lower incidence of complication （5.0% vs .35.0% ） （P＆lt;0 .05） .The score of range of motion（ROM） after treatment was lower than that before in group B（P＆lt;0 .05） .Besides ,the scores of WHOQOL-BREF and ROM in group A were higher than those in group B after treatment （P＆lt;0 .05 or P＆lt;0 .01） .Conclusion Artificial cervical disc replacement is effective and safe for the treatment of cervical spondylosis .

关 键 词：人工颈椎间盘 椎体间融合 颈椎病 

分 类 号：R687[医药卫生—骨科学]