颈动脉粥样硬化与高血压病视网膜病变的相关性  

Correlation between carotid atherosclerosis and hypertensive retinopathy

作　　者：蔡吉梧 

机构地区：[1]中山市黄圃人民医院眼科,广东中山528429

出　　处：《广州医科大学学报》2017年第1期56-58,共3页Academic Journal of Guangzhou Medical University

摘　　要：目的:分析颈动脉粥样硬化与高血压性视网膜病变的相关性。方法:选择我院内科收治的高血压患者125例分2组,A组(脉压<60 mmHg)65例和B组(脉压≥60 mmHg)60例。所有患者均进行彩色多普勒超声检查眼底视网膜血流动力学判断出现视网膜病变例数,观察两组患者颈动脉血管壁内膜-中层厚度(IMT),计算斑块Crouse积分,并检测两组患者血脂水平,包括胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),分析结果。结果:125例患者中经检测有57例存在视网膜病变,且B组(33例)明显多于A组(24例)(P<0.05),且B组IMT、斑块Crouse积分及斑块检出率均显著高于A组,且LDL-C水平高于A组,均具有显著性差异(P<0.05),且视网膜病变者均存在不同程度的颈动脉粥样硬化,具有一定的相关性(P<0.05)。结论:高血压患者存在血脂异常,高血压严重者更易诱发颈动脉粥样硬化,出现视网膜病变,临床应予以重视。Objective： To determine the correlation between carotid atberosclerosis and hypertensive retinopathy. Methods： A total of 125 patients with hypertension hospitalized in the Department of Internal Medicine in our hospital were included as the subjects in the study, and Group A （PP 〈 60 mmHg） 65 cases, Group B （PP ≥60 mmHg） 60 cases. The hemodynamics in fundus retina of all patients was examined by color Doppler ultrasound to determine the number of cases with retinopathy.The carotid intima-media thickness （IMT） was examined, and the plaque Crouse score was calculated.The levels of blood lipids including cholesterol （TC） , triglyceride （TG）, high-density lipoprotein cholesterol （ HDL-C）, low-density lipoprotein cholesterol （ LDL-C）, were determined, and the findings were analyzed. Results： Among the 125 cases, there were 57 cases of retinopathy, and the number of cases with retinopathy in group B （ n = 33 ） was significantly more than that in group A （n = 24） （P〈0.05）.The IMT, plaque Crouse score, plaque detection rate in group B were significantly higher than those in group A, and LDL-C level in group B was higher than that in group A, and there were significant differences （P 〈 0.05 ）. There were different degrees of carotid atherosclerosis in all patients with retinopathy,showing a certain correlation （P 〈 0.05 ）. Conclusion： There are dyslipidemia in patients with hypertension,and severe hypertension is more likely to induce carotid atherosclerosis and retinopathy, which should be paid attention to in the clinical settings.

关 键 词：颈总动脉粥样硬化 高血压性视网膜病变 视神经病变 

分 类 号：R543[医药卫生—心血管疾病]