海南地区汉族健康成年人骨密度CT定量研究  

Quantitative CT study of bone mineral density for Han nationalities healthy adults in Hainan province

作　　者：陈文清[1] 李建军[1] 陈峰[1] 刘光洪[1] 沈宁江[2] 郑进华[1] 马秀苗[1] 张武[1] 李一波[2] 

机构地区：[1]海南省人民医院CT室,海南海口570311 [2]海南省人民医院骨病科,海南海口570311

出　　处：《海南医学》2017年第20期3342-3345,共4页Hainan Medical Journal

基　　金：国家临床专科建设项目(编号:国卫办医函[2013]544号);海南省自然科学基金(编号:811173);海南省哲学社会科学规划课题(编号:HNSK(YB)15-33)

摘　　要：目的研究海南地区成年人椎体骨密度(BMD)与年龄和性别的关系,建立各年龄段BMD均值和与设备自带同性别BMD峰值比较的标准差(T-Score)均值,以及了解本地区各年龄段骨质疏松症(OP)的发生情况。方法使用定量CT(QCT)对海南省人民医院2006年7月至2016年12月的1 080例健康成年人体检者进行腰椎BMD检测,对不同性别不同年龄段BMD值和T-Score进行t检验和方差分析,不同性别不同年龄段的OP发生率进行χ2分析和相关分析。结果 60~69岁、70~79岁男女间的BMD和T-Score值比较差异均有统计学意义(P<0.05),在40~49岁、50~59岁、60~69岁、70~79岁男性组及女性组中,同性别不同年龄组的BMD和T-Score值比较差异也有统计学意义(P<0.05),并且随年龄的增长而递减;在男性和女性组中,不同年龄段及同年龄段男女之间的OP发生率比较差异均有统计学意义(P<0.05),年龄与OP发生率呈正相关关系(r男=0.527,r女=0.797)。结论男、女各年龄段的BMD和T-Score均值随年龄的增长而递减;男、女各年龄段的OP发生率随着年龄的增长而增加。Objective To establish the average centrums bone mineral density （BMD） of each age group, and the average value of T-Score difference between the average BMD and equivalent BMD peak, and to understand osteo-porosis （OP） incidence distribution in the region. Methods Quantitative CT （QCT） was used to examine and record the lumbar BMD of 1080 healthy adults who underwent physical examination in Hainan General Hospital from July 2006 to December 2016. T test and variance analysis were carried out on BMD and T-Score in different sex and age group. Chi square analysis and correlation analysis were performed on the incidence of OP in different sex and age group. Results There was significant difference in the BMD and T-Score between male and female of 60-69 and 70-79 years old （P〈0.05）. There were also significant differences in BMD and T-Score in different age groups of the same sex between male and female groups of 40-49, 50-59, 60-69, and 70-79 years old, and decreased with age. In the male and female groups, there was significant difference in the incidence of OP between different age groups and the same age group （P〈0.05）. Age was positively related to the incidence of OP （r=0.527 for male and r=0.797 for female）. Conclusion The average BMD and T-Score of males and females decreased with age. The incidence of OP for male and female in all ages increased with age.

关 键 词：海南 成年人 骨密度 年龄 性别 相关性 

分 类 号：R68[医药卫生—骨科学]