中华鳖多糖的药理作用研究  

Studies on pharmacological effects of Trionyx sinensis polysaccharides

作　　者：郑宝灿[1] 陈忠科[1] 鲁玉菱 

机构地区：[1]山东大学生物系

出　　处：《中国药学杂志》1991年第5期275-277,共3页Chinese Pharmaceutical Journal

摘　　要：中华鳖多糖(TSP,0.5,1.0或2.0g/kg×15～20d,po)能提高小鼠缺氧耐力和抗冷冻作用,可延长小鼠游泳时间,有抗疲劳作用。能提高小鼠PFC的溶血能力,促进抗体生成。能增加DTH反应。以0.5%或1.0%TSP Renger液浸泡蟾蜍坐骨神经腓肠肌标本,有增加收缩高度和画纹面积,延长持续收缩时间的作用。The abilities of resistant anoxia and cold-resis-tance in mice were improved by Trionyx sinensispolysaccharides (TSP) 0.5, 1.0 and 2.0 g/kg×15-20d, po. The experimental results showed that TSPhad the functions of anti-fatigue of swimming, cold-resistant and anti-anoxia. The hemolysis ability ofnormal mice plaque forming cells (PFC) was en-hanced, the production of antibodies promoted, andthe delayed type hypersensitivity (DTH) increased byTSP. When the sciatic nerve gastrocnemius of toadwas dipped in 0.5% and 1.0% TSP solution, itscontractive height and area of drawing lines were in-creased. The results suggested that the contraction ofsheletal muscle was enhanced and the fatigue preduc-tion and development were delayed by TSP.

关 键 词：中华鳖 多糖 药理 

分 类 号：R282.740.5[医药卫生—中药学]