达英35联合2%米诺地尔溶液治疗女性型脱发疗效观察  

The Clinical Efficacy of Diane-35 and Minoxidil in the Treatment of Female Pattern Hair Loss

作　　者：储小燕[1] 刘艳[1] 富志良[1] 芦桂青[1] 康莉[1] 毕志刚[1] 

机构地区：[1]南京医科大学附属明基医院南京明基医院皮肤科,江苏南京210019

出　　处：《中国美容医学》2017年第11期72-74,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:观察达英35联合2%米诺地尔溶液治疗女性型脱发的临床疗效和安全性。方法:将110例女性型脱发患者随机分成两组。试验组:55例,采用达英35联合2%米诺地尔溶液治疗;对照组:55例,仅外用2%米诺地尔溶液治疗。两组治疗12周后评价疗效及不良反应。结果:治疗12周后,试验组有效率为70.91%,高于对照组的43.64%,两组间差异有统计学意义(P<0.05);睾酮及脱氢表雄酮水平显著低于对照组,差异具有统计学意义(P<0.05)。两组间不良反应发生率比较无显著性差异(P>0.05)。结论:达英35联合2%米诺地尔溶液治疗女性型脱发疗效优于单用2%米诺地尔,且安全性好。Objective To observe the clinical effcacy and safety of Diane-35（Ethinylestradiol and Cyproterone Acetate Tablets） and minoxidil in the treatment of female pattern hair loss. Methods 110 patients with female pattern hair loss were randomly divided into two groups： the experimental group was treated with Diane-35 and minoxidil, while the control group was treated with minoxidil only. The effcacy and side effects was evaluated after treated 12-week treatment. Results After 12 weeks treatment, the total effective rates were 70.91% in the experiment group and 43.64% in the control group （P〈0.05）; the sera T and DHEA level of the experiment group Was signifcantly lower than that of the control group （P〈0.05）; There were no signifcant difference in side effective rate between two groups. Conclusion It is effective and safe for Diane-35 in combination with minoxidil in the treatment of female pattern hair loss.

关 键 词：达英35 米诺地尔 女性型脱发 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]