维生素D水平与男性血脂综合指数的关系  

作　　者：王莹[1] 司少艳[1] 任晔[1] 崔迪[1] 贾海英[1] 宋淑军[1] 

机构地区：[1]中国人民解放军第306医院放疗科,100101

出　　处：《浙江临床医学》2017年第12期2317-2318,共2页Zhejiang Clinical Medical Journal

摘　　要：目的探讨男性血中维生素D水平与血脂综合指数之间的关系。方法选取2013年1月至12月期间体检的健康男性817侧，留取空腹静脉血，测定血清25-羟维生素D的水平，检测血清总胆固醇、甘油三酯、低密度脂蛋白及高密度脂蛋白，计算出血脂综合指数。结果受试者25．羟维生素D水平平均为（53．56±21．83）nmol／L。维生素D缺乏组的血脂综合指数明显高于维生素D正常组。在校正了年龄、体重指数、空腹血糖、收缩压、舒张压等混杂因素的影响后，维生素D与血脂综合指数呈明显负相关，并且维生素D每升高1nmol／L，血脂综合指数值降低0．16。结论男性维生素D水平与血脂综合指数值关系密切。因此，维持人体正常维生素D水平可能对预防血脂紊乱相关疾病具有一定意义。Objective To explore the correlation between vitamin D levels with lipid comprehensive index in men. Methods In this study, 817 male cases who participated in physical examination in 306 Hospital of PLA were collected. The levels of 25-hydroxyvitamin D, total cholesterol, triglyceride, low density lipoprotein and high density lipoprotein were detected using fasting food blood samples, and then lipid comprehensive index was calculated. Results The average level of 25-hydroxyvitamin D was （ 53.56_＋21.83 ） nmol/Lin all subjects. Compared to the vitamin D sufficient group, the lipid comprehensive index value was significantly increased in vitamin D deficient group. The results showed that after adjusting confounding factors such as age, body mass index, fasting blood glucose, systolic blood pressure and diastolic blood pressure. Vitamin D had a negative relation with lipid comprehensive index value, furthermore, Per lnmol/L increase in the level of 25-hydroxyvitamin D was associated with a decrease of 0.16 in lipid comprehensive index value. Conclusions The serum 25-hydroxyvitamin D concentration is closely related to the lipid comprehensive index in men. Thereby, improving vitamin D status may have benefits on the protection of the dyslipidemia related diseases.

关 键 词：维生素D 血脂综合指数 冠心病 

分 类 号：R599.901[医药卫生—内科学]