基于赋权逼近理想值排序法的左氧氟沙星预防用药利用评价  

Drug use evaluation of levofloxacin prophylactic used in neonates based on weighted technique for order preference by similarity to an ideal solution method

作　　者：吴柳婷 罗洁丽[1] 黄艳芳[1] 白敦耀 陈娈 陈曼[2] 

机构地区：[1]武汉科技大学附属普仁医院药学部,武汉430081 [2]武汉市中医医院药学部,武汉430014

出　　处：《临床药物治疗杂志》2017年第9期51-55,共5页Clinical Medication Journal

摘　　要：目的:利用药物利用评价(drug use evaluation,DUE)的赋权逼近理想值排序法(technique for order preference by similarity to an ideal solution,TOPSIS)进行左氧氟沙星的预防用药评价。方法:结合DUE建立评价标准,运用基于属性的层次模型(attribute hierarchical mode,AHM)赋权法计算评价指标的相对权重,并运用TOPSIS进行数据处理以评价各医嘱与完全合理医嘱的距离,计算合理医嘱的比例,以评价抗菌药物预防用药合理性。结果:64份医嘱中完全合理的医嘱占66%(C_i=1,42份),基本合理医嘱占23%(0.8>C_i>0.6,15份),不合理医嘱占11%(C_i<0.6,7份)。结论:运用基于DUE的加权AHM的TOPSIS法对左氧氟沙星预防用药进行合理性评价是合理可行的。武汉科技大学附属普仁医院在左氧氟沙星的预防用药基本合理,但仍需改进。Objective： To use the weighted TOPSIS method（TOPSIS） for drug evaluation based on DUE of levofloxacin prophylactic used. Methods： In order to evaluate the rationality of prophylactic use of antibiotics, the evaluation indicators and evaluation criteria binding DUE was established, the relative weight of evaluation index by using attribute AHM weight method was calculated, the distance between medical records with perfectly logical records by the use of TOPSIS was evaluated, and the proportion of reasonable records was calculated. Results： Among the 64 medical records, there were 66% perfectly reasonable（C_i=1, 42 cases）, 23% basically reasonable（1C_i0.8, 15 cases）, and 11% unreasonable（C_i0.6,7 cases）. Conclusion： By using the weighted TOPSIS method based on DUE to evaluate the rationality of levofloxacin prophylactic used is reasonable and feasible. Levofloxacin prophylactic used in most applications is basically reasonable in Puren Hospital of Wuhan University of Sciencc and Technology which still need to be continual improvement.

关 键 词：基于属性的AHM赋权法 加权逼近理想值排序法 左氧氟沙星 预防用药 药物利用评价 

分 类 号：R979.9[医药卫生—药品]