扩张型心肌病患者心肺运动试验与漂浮导管检查指标的相关性  

The Correlation between Parameters of Cardiopulmonary Exercise Test and Floating Catheterization Examination in Patients of Dilated Cardiomyopathy

作　　者：张炜[1] 许海燕[1] 黄洁[1] 党爱民[1] 

机构地区：[1]北京协和医学院中国医学科学院国家心血管病中心阜外医院特需医疗中心,北京市100037

出　　处：《中国分子心脏病学杂志》2017年第5期2204-2206,共3页Molecular Cardiology of China

基　　金：基金项目:首都市民健康项目培育(Z141100002114029)

摘　　要：目的探讨扩张型心肌病患者心肺运动试验(Cardiopulmonary exercise test,CPET)与漂浮导管指标的相关性。方法入选40例住我院的扩张型心肌病患者,其中男性35例,女性5例,心功能Ⅱ级者7例,Ⅲ级者33例,平均年龄43.51±11.35岁。患者均行超声心动图、N末端B型脑钠肽前体(NT-proBNP)、CPET和漂浮导管检查,并收集CPET中峰值氧耗量(VO_2max)、无氧阈(AT)结果及漂浮导管中中心静脉压(CVP)、心脏指数(CI)、平均肺动脉压(mPAP)、肺毛细血管楔压(PCWP)、肺血管阻力(PVR)等资料,分析各指标的相关性。结果 CPET中VO_2max与漂浮导管检查中mPAP(r=-0.463,P<0.01)、PCWP(r=-0.519,P<0.01)呈负相关,与CI(r=0.397,P<0.05)呈正相关。结论 CPET中VO_2max是用来评价扩张型心肌病患者心功能的良好指标。Objective Texplore the correlation between parameters of cardiopulmonary exercise test and invasive hemodynamic examination with Swan-Ganz＇ s flowing balloon catheter in patients of dilated cardiomyopathy.Methods This study was a single-center study.40 cases with dilated cardiomyopathy hospitalized in our hospital were enrolled in,35 cases were male and 5 were female.Cardiac function for 7 cases were Ⅱ grade,33 cases were Ⅲ grade（New York classification）.The average age was 43.51±11.35 years old.40 patients underwent echocardiography,NT-proBNP,cardiopulmonary exercise testing and floating catheter examination.We collected VO2max,anaerobic threshold in cardiopulmonary exercise testing and CVP,PVR,CI,mPAP,PCWP in floating catheter examination.We analyzed the correlation of the parameters.Results VO2max in cardiopulmonary exercise testing was negative correlated with mPAP（r=-0.463,P〈0.01）,PCWP（r=-0.519,P〈0.01）,and was positive correlated with CI（r=0.397,P〈0.05） in floating catheter.Conclusion VO2max is a good indicator used to evaluate cardiac function of patients with dilated cardiomyopathy.

关 键 词：扩张型心肌病 心肺运动试验 漂浮导管 

分 类 号：R542.2[医药卫生—心血管疾病]