王小云辨治妇科痛证用药规律的数据挖掘  

A Data Mining Research on Herbal Administration Regularity of Professors WANG Xiao-yun's Experience for Gynecologic Pain Syndrome

作　　者：叶润英[1] 翁衡[1] 王华菊 王小云[1] 

机构地区：[1]广东省中医院,广东广州510105

出　　处：《中医药导报》2017年第21期39-42,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：广东省科学技术厅资助项目(2014A020221039);项目名称:面向传承发展中医药古籍文献本体知识库服务平台

摘　　要：目的:研究挖掘王小云治疗妇科痛证的治疗及用药规律。方法:选取王小云2013年9月至2016年3月门诊诊治的妇科痛证患者137人次共316诊次张中药处方。利用"中医药大数据服务平台"的文献本体知识构建与挖掘服务,构建了中药性、味、归经、功效主治以及专科病、证等领域知识元组成的处方用药知识库,开展了结合领域知识的包括核心方频繁项集以及主题模型挖掘等方法的多维多层次关联分析。结果:妇科痛证的证型常见有气滞血瘀证、湿瘀互结证、寒凝血瘀证、湿热瘀阻证、肾虚血瘀证。组方用药最少用6味药,最多9味。结论:滞、瘀、寒是妇科痛证的主要病因,不通则痛是其主要病机。王小云治疗妇科痛证,常用方法是理气行滞、活血化瘀、温阳驱寒。Objective： To study the herbal administration regularity of Professors WANG Xiao-yun＇s experience for treating gynecologic pain syndrome. Methods： Between December 2013 and March 2016, a total of 316 traditional Chinese medicine （TCM） prescriptions for 137 patients with gynecologic pain syndrome prescribed by Professor WANG Xiao-yun from the Gynecology Outpatient Clinic were included. The prescription and medication knowledge base including property, flavor, channel tropism, efficacy, and indications for TCM, as well as TCM syndrome of gynecologic pain syndrome, was constructed. This knowledge base was aided by the literature ontology knowledge construction and mining services provided by the TCM data service platform. A multi-dimensional, multi-level association analysis was carried out using frequent item set and topic model mining, and combining the domain knowledge. Results： The most common TCM syndromes seen in the gynecologic pain syndrnme we~ Qi stagnancy and blood stasis, phlegm-damp and blood stasis, cold coagulation and blood stasis, stagnant dampness-heat and kidney deficiency and blood stasis syndrome. The prescription includes 6 to 9 herbs. Conclusion： Qi stagnation, blood stasis, and cold were the most common causes of gynecologic pain syndrome. Pain caused by stagnation was the major pathogenesis. The basic principles used by Professor WANG Xiao-yun on treating gynecologic pain syndrome were regulating Qi stagnancy, activating blood circulation, warming Yang and dispelling the cold.

关 键 词：王小云 名医传承 数据挖掘 妇科痛证 

分 类 号：R249[医药卫生—中医临床基础]