阿加曲班联合尤瑞克林治疗进展性脑梗死患者临床观察  

Clinical observation on treating progressive cerebral infarction with argatroban plus tramadol

作　　者：王胜英[1] 李高华[1] 满彦杰[1] 

机构地区：[1]抚顺矿务局总医院,辽宁抚顺113008

出　　处：《中医临床研究》2017年第27期42-44,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察阿加曲班联合尤瑞克林治疗进展性脑梗死患者的临床疗效。方法:选择100例脑梗死患者参与本次研究,采用随机分组法将患者分为治疗组(阿加曲班联合尤瑞克林治疗)和对照组(仅用尤瑞克林治疗),每组患者例数均为50例。分析经过不同方法治疗后,患者的治疗效果。结果:治疗组治疗总有效率高于对照组,差异显著(P<0.05),治疗组神经功能缺损评分情况优于对照组患者,差异显著(P<0.05)。所有患者在治疗期间均未发生脑出血等严重的不良反应,组间数据比较差异无统计学意义(P>0.05)。结论:阿加曲班联合尤瑞克林治疗进展性脑梗死,与单纯用药治疗方法相比,效果更显著,能够减轻患者的神经功能缺损症,且不良反应较少,值得临床广泛应用。Objective： To observe the clinical efficacy of argatroban combined with tramadol on progressive cerebral infarction. Methods： 100 cases of cerebral infarction were divided into the treatment group （received argatroban combined with tramadol treatment） and the control group （was treated only with tramadol）, with 50 cases in each group. The treatment effect was analyzed after different methods. Results： The total efficiency in the treatment group was higher than that in the control group, the difference was significant （P〈0.05）; the neural function defect score in the treatment group was better than that in the control group, the difference was significant （P〈0.05）. All patients during treatment showed no cerebral hemorrhage and other serious adverse reaction. The data was compared between the groups, which showed no significant difference （P〉0.05）. Conclusion： Argatroban combined with tramadol was more significantly effective in treating progressive cerebral infarction compared with simple adverse reactions, and is worthy of wide clinical application. medication, could reduce the neurological deficit of patients, with fewer adverse reactions, and is worthy of wide clinical application.

关 键 词：阿加曲班 尤瑞克林 进展性脑梗死 疗效 安全性 

分 类 号：R255.2[医药卫生—中医内科学]