雷公藤甲素及其注射液的稳定性研究  

Study On the stability of triptolide and its injection

作　　者：张海浪[1] 邓思珊[1] 

机构地区：[1]福建省医学科学研究所

出　　处：《中国药学杂志》1991年第8期478-479,共2页Chinese Pharmaceutical Journal

摘　　要：本文采用高效液相色谱法测定雷公藤甲素的含量,并对雷公藤甲素及其注射液的稳定性进行了研究,结果表明,雷公藤甲素原料的热稳定性好,在溶液中最大稳定pH值为4,其注射液在室温(25℃)的有效期为4个月,低温冷藏(10℃)的有效期为2年。The Stability of triptolide injection was studiedby high performance liquid chromatography. It wasfound that both pH and temperature were the mainfactors affecting the stability. Triptolide is stable insolutions at pH 4. The injection is stable for fourmonths at room temperature (25℃) and two yearsat low temperature (10℃).

关 键 词：雷公藤甲素 注射液 稳定性 

分 类 号：R927.11[医药卫生—药学]