肿瘤患者血清25-(OH)D水平测定的临床意义  

Clinical Significance of Detecting Serum 25-Hydroxyvitamin D in Tumor Patients

作　　者：韦小荣 黄丽秀 黄文渊 詹丹 刘晓艳 

机构地区：[1]广西医科大学附属武鸣医院检验科,广西南宁530199

出　　处：《中国继续医学教育》2017年第28期17-18,共2页China Continuing Medical Education

基　　金：国家科技支撑计划(名称:863计划;子课题:2015B AI32H00)

摘　　要：目的观察肿瘤患者血清25-(OH)D水平并探讨其临床意义。方法收集我院116例肿瘤患者为观察组和健康体检者116例为对照组,用电化学发光法检测肿瘤患者和健康对照者血清中25-(OH)D水平。结果观察组血清25-(OH)D水平低于对照组,差异有统计学意义(P=0.000);不同类型肿瘤患者之间的血清25-(OH)D水平对比,差异无统计学意义(P=0.085)。结论血清25-(OH)D水平降低与肿瘤存在着密切的联系,其结果对研究肿瘤的发生发展机理以及新的诊疗方法具有不可忽视的潜在价值。Objective To observe the serum levels of 25-（OH） D in patients with tumor and to explore its clinical significance. Methods 116 cases of cancer patients in our hospital were selected as the observation group and 116 cases of health examination as the control group. The level of serum 25-（OH） D in the of the tumor patients and healthy controls was detected by electrochemiluminescence. Results The levels of serum 25-（OH） D in obversion group were significantly lower than those in the control group（P=0.000）. There was no significant difference in serum 25-（OH） D levels between patients with different types of tumors（P=0.085）. Conclusion The decrease of serum 25-（OH） D levels is closely related to the tumor, and the results can＇t be ignored for the study of the pathogenesis and development of tumors and new methods of diagnosis and treatment.

关 键 词：肿瘤 血清25-(OH)D 电化学发光法 维生素D缺乏 

分 类 号：R446[医药卫生—诊断学]